IL PORTALE per la RICERCA dei DIPARTIMENTI

I. Rimoldi, E. Cesarotti, D. Zerla, R. Gandolfi (2011) "3-(Hydroxy(phenyl)methyl)azetidin-2-ones obtained via catalytic asymmetric hydrogenation or by biotransformation"

F. Clerici, A. Contini, M.L. Gelmi, S. Pellegrino (2011) "A New Series of Organocatalysts for Diels-Alder Cycloaddition Reactions and Theoretical Analysis"

A. Gazzaniga, M. Cerea, A. Foppoli, A. Maroni, L. Zema (2011) "A novel injection-molded capsular device for oral pulsatile delivery based on swellable/erodible polymers"

A. Sparatore (2011) "ACS6, a Hydrogen sulfide-donating derivative of sildenafil, inhibits homocysteine-induced apoptosis by preservation of mitochondrial function"

A. Sparatore (2011) "ACS84, a novel hydrogen sulfide-releasing compound, protects against amyloid ß-induced cell cytotoxicity"

G. Aldini (2011) "Advanced analytical strategies for recombinant therapeutic proteins"

S. Romeo (2011) "Alcohols immobilization onto 2-chlorotritylchloridenext term resin under microwave irradiation"

G. Beretta (2011) "An analytical and theoretical approach for the profiling of the antioxidant activity of essential oils: the case of Rosmarinus officinalis L."

G. Aldini, A. Pedretti, M. Carini (2011) "An integrated high resolution mass spectrometric and informatics approach for the rapid identification of phenolics in plant extract"

F. Cilurzo, F. Selmin, C.G.M. Gennari, P. Minghetti, L. Montanari (2011) "An investigation into silk fibroin conformation in composite materials intended for drug delivery"

P. Minghetti, P. Rocco (2011) "Biosimilars and Regulatory Authorities"

I. Rimoldi, M. Pellizzoni, G. Facchetti, D.S. Zerla, R. Gandolfi (2011) "Chemo- and biocatalytic strategies to obtain phenylisoserine, lateral chain of taxol by asymmetric reduction"

G. Vistoli, A. Pedretti (2011) "Chemodiversity and molecular plasticity: recognition processes as explored by property spaces"

P. Minghetti, F. Selmin, A. Casiraghi (2011) "Compassionate-use programmes: an alternative treatment for patients in need"

G. Beretta (2011) "Conformation of the tridimensional structure of 1,2,3,4,6-pentagalloyl-ß-D-glucopyranose (PGG) by (1)H NMR, NOESY and theoretical study and membrane interaction in a simulated phospholipid bilayer: a first insight"

A. Arnoldi (2011) "Cross-reactivity between peanut and lupin proteins"

S. Romeo (2011) "Design and synthesis of protein–protein interaction mimics as Plasmodium falciparum cysteine protease, falcipain-2 inhibitors"

C. Dallanoce, C. Matera, G. Grazioso, M. De Amici, C. De Micheli (2011) "Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl-¿2-Isoxazoline Derivatives as Potent and Selective Agonists of a7 Nicotinic Acetylcholine Receptors"

M. Orioli, G. Vistoli, A. Pedretti, M. Carini, G. Aldini (2011) "Design, synthesis, ADME properties, and pharmacological activities of ß-alanyl-D-histidine (D-carnosine) prodrugs with improved bioavailability"

Roberta Ettari (2011) "Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors"

F. Cilurzo, P. Minghetti, C.G.M. Gennari, L. Montanari (2011) "Diclofenac fast-dissolving film : suppression of bitterness by a taste-sensing system"

P. Conti, L. Tamborini, A. Pinto, C. De Micheli (2011) "Drug Discovery Targeting Amino Acid Racemases"

G. Roda (2011) "Effect of chemical composition of SBA-15 on the adsorption and catalytic activity of a-chymotrypsin"

A. Sparatore (2011) "Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity"

G. Grazioso, C. Dallanoce, C. De Micheli, M. De Amici (2011) "Engineering of a-conotoxin MII-derived peptides with increased selectivity for native a6ß2* nicotinic acetylcholine receptors"

R. Gandolfi (2011) "Enzymatic hydrolysis of capsaicins for the production of vanillylamine using ECB deacylase from Actinoplanes utahensis"

C. Lammi (2011) "Evidence for the existence of a specific g protein-coupled receptor activated by guanosine"

A. Pedretti, G. Vistoli (2011) "Exploring the activation mechanism of TRPM8 channel by targeted MD simulations"

M. Carini, G. Aldini (2011) "Fibrosis, enzymatic and non-enzymatic cross-links in hypertensive heart disease"

Roberta Ettari (2011) "Formation of 3-Aminofuran-2-(5H)-ones and 3-Amino-1H-pyrrole-2,5-diones by Rearrangement of Isoxazolidines"

A. Pedretti, G. Aldini, G. Vistoli (2011) "Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping"

M. Dell'Acqua, G. Abbiati, E. Rossi (2011) "From domino to multicomponent : synthesis of dihydroisobenzofurans"

G. Fico (2011) "From vineyard to glass : agrochemicals enhance the melatonin and total polyphenol contents and antiradical activity of red wines"

R. Ettari (2011) "Glutamate Binding-Site Ligands of NMDA Receptors"

A.C. Sparatore (2011) "H2S releasing aspirin protects amyloid beta induced cell toxicity in BV-2 microglial cells"

M. Pallavicini, C. Bolchi, L. Fumagalli, E. Valoti (2011) "Highly efficient racemisation of a key intermediate of the antibiotic moxifloxacin"

G. Abbiati, M. Dell'Acqua, E. Rossi (2011) "InCl3-assisted one-pot synthesis of 1-aminocarbazoles"

F. Cilurzo, F. Selmin, P. Minghetti, L. Montanari (2011) "Injectability evaluation : an open issue"

E. Beccalli (2011) "Intramolecular Oxidative Pd(II)-Catalyzed Alkoxylation of 3-Aza-5-alkenols with O2 as Sole Oxidant: Mild Conditions for the Synthesis of 1,4-Oxazine Derivatives"

A. Arnoldi (2011) "Legumes are valuable sources of tocopherols"

M. Carini, G. Aldini (2011) "Mass Spectrometric Strategies and their Applications for Molecular Mass Determination of Recombinant Therapeutic Proteins"

Roberta Ettari (2011) "Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: The Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives"

M. Dell'Acqua (2011) "Metal-Free Direct Arylations of Indoles and Pyrroles with Diaryliodonium Salts"

F. Selmin, M. Carini, F. Cilurzo, G. Aldini (2011) "Methylprednisolone-loaded PLGA microspheres: A new formulation for sustained release via intra-articular administration. A comparison study with methylprednisolone acetate in rats"

S. Villa (2011) "Modeling and Spectroscopic Studies of Synthetic Diazabicyclo Analogs of the HIV-1 Inhibitor BMS-378806 and Evaluation of Their Antiviral Activity"

G. Grazioso (2011) "Molecular dynamics simulations of the Salmonella typhi Vi antigenic polysaccharide and effects of the introduction of a zwitterionic motif"

E. Pini (2011) "Nanocrystals as tool to improve piroxicam dissolution rate in novel orally disintegrating tablets"

C. Dallanoce, G. Grazioso, C. Matera, M. De Amici, C. De Micheli (2011) "New spirocyclic ¿2-isoxazoline derivatives related to selective agonists of a7 neuronal nicotinic acetylcholine receptors"

Vistoli G (2011) "New synthesis of 6[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid and evaluation of the influence of adamantyl group on the DNA binding of a naphthoic retinoid"

S. Romeo (2011) "Novel biotinylated bile acid amphiphiles : micellar aggregates formation and interaction with hepatocytes"

A. Arnoldi (2011) "Nutritional and nutraceutical characteristics of lupin protein"

S. Pellegrino (2011) "On the Stability of Polyalanine Secondary Structures: The Role of the Polyproline II Helix"

M.D. Del Curto, A. Maroni, L. Palugan, L. Zema, A. Gazzaniga (2011) "Oral delivery system for two-pulse colonic release of protein drugs and protease inhibitor/absorption enhancer compounds"

E. Beccalli (2011) "Palladium-catalyzed C-N bond formation via direct C-H bond functionalization. Recent developments in heterocyclic synthesis"

G. Grazioso (2011) "Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors"

G. Beretta, G. Fico (2011) "Phenolic compounds from Achillea millefolium L. and their bioactivity"

G. Fico (2011) "Primula spectabilis Tratt. aerial parts: morphology, volatile compounds and flavonoids"

F. Meneghetti (2011) "Proprotein convertase subtilisin/kexin type 9 (PCSK9): from structure-function relation to therapeutic inhibition"

G. Aldini, M. Orioli, M. Carini (2011) "Protein modification by acrolein: relevance to pathological conditions and inhibition by aldehyde sequestering agents"

F. Cilurzo, F. Selmin, P. Minghetti (2011) "Pyrogallic acid-PLGA conjugate as new biodegradable material suitable for final sterilization by irradiation"

A. Sparatore (2011) "Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Potent Inhibitors of Acetyl- and Butyrylcholinesterase with Potential in Alzheimer's Disease"

L. Tamborini, A. Pinto, P. Conti, C. De Micheli (2011) "Regioselective Preparation of Functionalized Isoxazoline Derivatives, Key Intermediates in the Synthesis of Selective NMDA Receptor Antagonists"

P. Minghetti (2011) "Regulations applicable to plant food supplements and related products in the European Union"

A. Sparatore (2011) "S-diclofenac protects against doxorubicin-induced cardiomyopathy in mice via ameliorating cardiac gap junction remodeling"

G. Vistoli, G. Aldini, M. Carini (2011) "Screening of fibrillogenesis inhibitors of ß2-microglobulin : integrated strategies by mass spectrometry capillary electrophoresis and in silico simulations"

D. Masciocchi, A. Gelain, S. Villa, F. Meneghetti, D. Barlocco (2011) "Signal transducer and activator of transcription (Stat) 3 : a promising target for anticancer therapy"

M. Dell'Acqua, G. Abbiati, E. Rossi (2011) "Silver-catalysed intramolecular cyclisation of 2-alkynylacetophenones and 3-acetyl-2-alkynylpyridines in the presence of ammonia"

A. Pedretti (2011) "Simulation of urea-induced protein unfolding: a lesson from bovine ß-lactoglobulin"

E. Beccalli (2011) "Solvent-Free, Microwave-Assisted N-Arylation of Indolines by using Low Palladium Catalyst Loadings"

C. La Rosa (2011) "Stereoselective synthesis of ß-substituted-l-threonines from enantiopure 5-acetyl-2-isoxazolines"

N. Gaggero (2011) "Stereoselective thio-Michael addition to chalcones in water catalyzed by bovine serum albumin"

G. Fico (2011) "Study on secondary metabolite content of Helleborus niger L. leaves"

P. Conti, L. Tamborini, A. Pinto (2011) "Synthesis and Biochemical Evaluation of ¿2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors"

P. Conti, A. Pinto, L. Tamborini, C. De Micheli (2011) "Synthesis and in vitro/in vivo Evaluation of the Antitrypanosomal Activity of 3-Bromoacivicin, a Potent CTP Synthetase Inhibitor"

A. Pedretti, G. Vistoli (2011) "Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the a1-adrenoceptors"

A. Pinto, P. Conti, G. Grazioso, L. Tamborini, C. De Micheli (2011) "Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors"

E. Beccalli, M.L. Gelmi, A. Contini (2011) "Synthesis, Structural and Biological Evaluation of Bis-Heteroarylmaleimides and Bis-Heterofused Imides"

G. Abbiati, E. Rossi (2011) "Tandem imination/annulation of g- and d-ketoalkynes in the presence of ammonia/amines"

A. Pedretti, G. Vistoli (2011) "The approach of conformational chimeras to model the role of proline-containing helices on GPCR mobility: the fertile case of Cys-LTR1"

A. Arnoldi (2011) "The artificial intelligence-based chemometrical characterization of genotype/chemotype of Lupinus albus and Lupinus angustifolius permits their identification and potentially their traceability"

G. Aldini, M. Orioli, G. Vistoli, M. Carini (2011) "The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats"

P. Conti (2011) "The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death"

G. Fico (2011) "The presence of melatonin in grapevine (Vitis vinifera L.) berry tissues"

A. Sparatore (2011) "Therapeutic potential of new hydrogen sulfide-releasing hybrids"

C. Bolchi, M. Pallavicini, G. Chiodini, L. Fumagalli, E. Valoti (2011) "Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase"

C. Bolchi, L. Fumagalli, G. Vistoli, E. Valoti, M. Pallavicini (2011) "Unichiral 2-(2'-Pyrrolidinyl)-1,4-benzodioxanes: the 2R,2'S Diastereomer of the N-Methyl-7-hydroxy Analogue Is a Potent a4ß2- and a6ß2-Nicotinic Acetylcholine Receptor Partial Agonist"

G. Aldini, M. Orioli, P. Minghetti, M. Carini (2011) "Urinary profile of methylprednisolone acetate metabolites in patients following intra-articular and intramuscular administration"

G. Vistoli, A. Pedretti (2011) "Virtual screening approach for the identification of potential Citrus tristeza virus inhibitors"

M. CARINI (2011) "What we know about oxidative stress in patients with chronic kidney disease on dialysis-clinical effects, potential treatment, and prevention"

L. Zema, L. Palugan, A. Gazzaniga (2011) "A high strenght mesalamine multiple-unit dosage form intended for ileo-colonic delivery"

F. Cilurzo, C.G.M. Gennari, P. Minghetti, F. Selmin, L. Montanari (2011) "An oromucosal bioadhesive suspension for prolonged release of clobetasol propionate"

C. De Micheli, P. Conti, A. Pinto, L. Tamborini (2011) "From potent AMPA/KA agonists to either selective NMDA antagonists or to inhibitors of the glutamate transporters"

A. Sparatore (2011) "Identification of hydrogen-sulfide releasing compounds as novel antiresorptive and antitumour agents"

A. Gazzaniga, A. Foppoli, M. Cerea, G. Loreti, E. Macchi, A. Maroni (2011) "In vivo evaluation of an oral pulsatile delivery system prepared by Injection-Molding"

M.D. Del Curto, A. Maroni, L. Zema, M. Cerea, A. Foppoli, A. Gazzaniga (2011) "Multiple-unit formulation for pulsatile and colon delivery : preparation and in vitro characterization"

A. Casiraghi, S. Franzè, P. Minghetti (2011) "OTTIMIZZAZIONE DI UNA PREPARAZIONE SEMISOLIDA CONTENENTE LIDOCAINA"

M. Cerea, L. Palugan, G. Loreti, E. Macchi, M.D. Del Curto, A. Gazzaniga (2011) "Preparation of HPMC/Pectin-Coated Systems for Oral Colon delivery"

F. Selmin, F. Cilurzo, S. Franzè, P. Minghetti (2011) "Regenerated keratin films : an alternative to human skin in in vitro drug permeability studies"

A. Casiraghi, P. Minghetti (2011) "TRATTAMENTO DI PAZIENTI AFFETTI DA SCABBIA CON PERMETRINA SOLUZIONE IN OLIO DI VASELINA"

P. Conti (2011) "The Glial Glutamate Transporter 1 (GLT1) is Expressed by Pancreatic beta-Cells and Prevents Glutamate-Induced beta-Cell Death"