IL PORTALE per la RICERCA dei DIPARTIMENTI

Marco Radi (2011) "A Domino Microwave-Assisted Protocol for the Synthesis of 2,6-Disubstituted Pyrimidinones"

L. Elviri (2011) "A voltammetric immunosensor based on nanobiocomposite materials for the determination of alpha-fetoprotein in serum"

Marco Radi (2011) "ATP-Competitive Inhibitors of mTOR: An Update"

L. Amori, G. Costantino (2011) "Addressing the Conformational Flexibility of Serine Racemase by Combining Targeted Molecular Dynamics, Conformational Sampling and Docking Studies"

A. Caretta (2011) "Aggregates of cAMP-dependent kinase isoforms characterize different areas in the developing central nervous system of the chicken, Gallus gallus."

F. Zani (2011) "Antimicrobial activity of organotin(IV) complexes with the ligand benzil bis(benzoylhydrazone) and 4,4'-bipyridyl as coligand"

M Mor, A Lodola (2011) "Application of a SCC-DFTB QM/MM approach to the investigation of the catalytic mechanism of fatty acid amide hydrolase. "

Sartori A, Dell'Amico L, Curti C, Battistini L, Zanardi F (2011) "Aqueous and Solvent-Free Uncatalyzed Three-Component Vinylogous Mukaiyama-Mannich Reactions of Pyrrole-Based Silyl Dienolates"

A. Rossi, P. Colombo (2011) "Assemblage of drug release modules: Effect of module shape and position in the assembled systems on floating behavior and release rate"

P. Colombo, F. Sonvico (2011) "Assembled modules technology for site-specific prolonged delivery of norfloxacin"

P. Vicini, M. Incerti (2011) "Benzisothiazolyliminothiazolidin-4-ones with chondroprotective properties: searching for potent and selective inhibitors of MMP-13."

F. Vacondio, C. Silva, A. Lodola, C. Carmi, S. Rivara, M. Mor (2011) "Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: steric effects of N-alkyl chain on rat plasma and liver stability "

E. Barocelli (2011) "Bitter taste receptors (T2Rs) expression and regulation in the gastrointestinal tract in mice."

M. Mor, S. Rivara (2011) "Bivalent ligand approach on N-{2-[(3 -methoxyphenyl)methylamino]ethyl}acetamide: Synthesis, binding affinity and intrinsic activity for MT1 and MT2 melatonin receptors."

A. Mozzarelli (2011) "Bound Water at Protein-Protein Interfaces: Partners, Roles and Hydrophobic Bubbles as a Conserved Motif"

Sonvico F., Balducci A.G. (2011) "Brain distribution of ribavirin after intranasal administration"

E. Favari, F. Zimetti, F. Bernini (2011) "CHOLESTEROL EFFLUX POTENTIAL OF SERA FROM DIABETIC PATIENTS: CLINICAL APPLICATIONS"

CURTI C., BATTISTINI L., SARTORI A., LODOLA A., MOR M., ZANARDI F. (2011) "Catalytic, Asymmetric Hypervinylogous Mukaiyama Aldol Reactions of Extended Furan-Based Silyl Enolates"

Massimiliano Tognolini (2011) "Chemical Composition, NMR Fingerprinting, Mutagenic/antimutagenic and Functional Properties of Commercial South-African Pelargonium capitatum (L.) L’Herit. (Geraniaceae) Essential Oil"

R. Bettini (2011) "Chemical composition and bioactivity of Citrus medica L. cv. Diamante essential oil obtained by hydrodistillation, cold-pressing and Supercritical Carbon Dioxide extraction"

Andrea Mozzarelli (2011) "Chemogenomics of pyridoxal 5'-phosphate dependent enzymes"

COLOMBO P (2011) "Chronic obstructive pulmonary disease: patho-physiology, current methods of treatment and the potential for simvastatin in disease management"

Marco Radi (2011) "Computational techniques are valuable tools for the discovery of protein–protein interaction inhibitors: The 14-3-3s case"

Lisa Elviri (2011) "Copper Binding Agents Acting as Copper Ionophores Lead to Caspase Inhibition and Paraptotic Cell Death in Human Cancer Cells"

A. Lodola, M. Mor (2011) "Covalent Inhibitors of Fatty Acid Amide Hydrolase: A Rationale for the Activity of Piperidine and Piperazine Aryl Ureas"

Marco Radi (2011) "Design, Synthesis, Biological Activity, and ADME Properties of Pyrazolo[3,4-d]pyrimidines Active in Hypoxic Human Leukemia Cells: A Lead Optimization Study"

CURTI C., BATTISTINI L., SARTORI A., ZANARDI F. (2011) "Diastereo- and Enantioselective Catalytic Vinylogous Mukaiyama-Mannich Reactions of Pyrrole-Based Silyl Dienolates with Alkyl-Substituted Aldehydes"

G. Costantino (2011) "Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ"

A. Mozzarelli (2011) "Drug Discovery Targeting Amino Acid Racemases"

S.Pescina, C. Padula, P. Santi, S. Nicoli (2011) "EFFECT OF FORMULATION FACTORS ON THE TRANS-SCLERAL IONTOPHORETIC AND POST-IONTOPHORETIC TRANSPORTS OF A 40KDa DEXTRAN IN VITRO"

S. Bruno, A. Mozzarelli (2011) "Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes"

A. Balducci, F. Sonvico, P. Colombo (2011) "Enhancing ribavirin nose-to-brain delivery by powder formulation for veterinary CNS infections"

C. Carmi, A. Lodola, S. Rivara, F. Vacondio, M. Mor (2011) "Epidermal Growth Factor Receptor Irreversible Inhibitors: Chemical Exploration of the Cysteine-Trap Portion"

B. Campanini, A. Mozzarelli (2011) "Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy"

Mozzarelli A (2011) "Exploring and exploiting allostery: Models, evolution, and drug targeting"

A. Mozzarelli (2011) "Exploring methionine gamma-lyase structure-function relationship via microspectrophotometry and X-ray crystallography."

G. Costantino (2011) "Extending SAR of bile acids as FXR ligands: discovery of 23-N-(carbocinnamyloxy)-3a,7a-dihydroxy-6a-ethyl-24-nor-5ß-cholan-23-amine."

Favari E., Ronda N., Bernini F. (2011) "Free cholesterol alters macrophage morphology and mobility by an ABCA1 dependent mechanism"

C. Compari, E. Fisicaro (2011) "HIV-1 IN strand transfer inhibitors: a focus on metal binding"

E. Fisicaro, C. Compari (2011) "HYDROPHOBIC HYDRATION PROCESSES. THERMAL AND CHEMICAL DENATURATION OF PROTEINS"

P. Vicini, M. Incerti (2011) "Heteroarylimino-4-thiazolidinones as inhibitors of cartilage degradation"

S. Bruno, A. Mozzarelli (2011) "Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana"

B. Campanini, A. Mozzarelli (2011) "Human kynurenine aminotransferase II: reactivity with substrates and inhibitors"

G. Lusardi, F. Bernini, I. Zanotti (2011) "IN VIVO TREATMENT WITH CYCLOSPORINE A INCREASES EFFLUX POTENTIAL OF MOUSE PLASMA VIA ATP-BINDING CASSETTE TRANSPORTER ABCA1"

Marco Radi (2011) "Identification of Potent c-Src Inhibitors Strongly Affecting the Proliferation of Human Neuroblastoma Cells"

L. Elviri (2011) "Improved silica xerogel film processing for MALDI-TOF-MS quantitative analysis of peptides and small molecules"

C. Padula, S. Nicoli, P. Santi (2011) "In vitro evaluation of bioadhesive films containing ibuprofen"

Barocelli E (2011) "Inflammatory proteases released in a mouse model of intestinal ischemia"

P. COLOMBO (2011) "Inhaled Drug Therapy for Treatment of Tuberculosis"

S. Barbieri, F. Sonvico, P. Colombo (2011) "Interaction of chitosan/lecithin nanoparticles with the rat intestinal tissue"

NICOLI S. (2011) "Interpretation of the human skin biotribological behaviour after tape stripping"

C. COMPARI, E. FISICARO (2011) "Investigating the Role of Metal Chelation in HIV-1 Integrase Strand Transfer Inhibitors"

L. Elviri (2011) "Investigation of novel sol-gel hydrophobic surfaces for desorption electrospray ionization-mass spectrometry analysis"

A.G. Balducci, F. Buttini, P. Colombo, A. Rossi (2011) "Layered lipid microcapsules for mesalazine delayed-release in children"

Bruno S, Mozzarelli A (2011) "Ligand migration and hexacoordination in type 1 non symbiotic rice hemoglobin"

F. Vacondio, C. Silva, L. Flammini, E. Barocelli, M. Mor (2011) "Liquid chromatography-mass spectrometric method for determination of the non-imidazole H(3) -receptor antagonist UPR1056 in rat plasma. "

Giorgio C, Hassan Mohamed I, Flammini L, Barocelli E, Incerti M, Lodola A, Tognolini M. (2011) "Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation."

S. Bruno, A. Mozzarelli (2011) "Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes."

I. Zanotti, F. Bernini (2011) "Macrophage, But Not Systemic, Apolipoprotein E Is Necessary for Macrophage Reverse Cholesterol Transport In Vivo"

S. Rivara, M. Mor (2011) "Melatonin receptor agonists: new options for insomnia and depression treatment."

M. Mor (2011) "Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines"

S. Bruno, A. Mozzarelli (2011) "Modulation of expression and polymerization of hemoglobin Polytaur, a potential blood substitute"

C. Beato, G.Costantino (2011) "Molecular dynamics simulations and docking studies on 3D models of the heterodimeric and homodimeric 5-HT(2A) receptor subtype."

Marco Radi (2011) "New insights into small-molecule inhibitors of Bcr-Abl"

Battistini L, Dell'Amico L, Sartori A, Curti C, Zanardi F (2011) "On-Water Vinylogous Mukaiyama-Michael Addition of Heterocyclic 2-Silyloxydienes to 1,2-Diaza-1,3-dienes: One-Pot Three-Step Entry to Functionality-Rich Pyrroles"

S. Bruno, A. Mozzarelli (2011) "Oxygen and Nitric Oxide Rebinding Kinetics in Nonsymbiotic Hemoglobin AHb1 from Arabidopsis thaliana"

S. Bruno, A. Mozzarelli (2011) "Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport."

F. Zani (2011) "Palladium(II) complexes of quinolinylaminophosphonates: synthesis, structural characterization, antitumor and antimicrobial activity"

F. Sonvico (2011) "Pectin Matrix as Oral Drug Delivery Vehicle for Colon Cancer Treatment"

Elviri L. (2011) "Phytochelatins govern zinc/copper homeostasis and cadmium detoxification in Cuscuta campestris parasitizing Daucus carota"

S. Bruno (2011) "Polymerization of hemoglobins in Arctic fish: Lycodes reticulatus and Gadus morhua"

I Hassan Mohamed, C Giorgio, L Flammini, E Barocelli, M Tognolini (2011) "Polyphenol rich botanicals used as food supplements interfere with EphA2-ephrinA1 system."

S. Rivara, M. Mor (2011) "Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand."

S. Bruno, A. Mozzarelli (2011) "Protein crystal microspectrophotometry"

A. Caretta (2011) "Protein kinase A in cancer"

Paredi G, Mozzarelli A. (2011) "Proteomic analysis of pork meat in the production of cooked ham"

G. Lusardi, F. Bernini, I. Zanotti (2011) "ROLE OF APOLIPOPROTEIN E IN CELLULAR CHOLESTEROL EFFLUX"

Bernini F (2011) "Report of the 33rd annual conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010"

M. Radi (2011) "Src Kinase Inhibitors: An Update on Patented Compounds"

S. Bruno (2011) "Structural heterogeneity and ligand gating in ferric Methanosarcina acetivorans protoglobin mutants."

A. Rossi, F. Sonvico, P. Colombo (2011) "Structural surface changes and inflammatory responses against alginate-based microcapsules after exposure to human peritoneal fluid"

Franca Zani, Matteo Incerti, Paola Vicini (2011) "Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents"

L. Elviri (2011) "Synthesis, Structural Characterization, and Magnetic Properties of the Heteroleptic Dinuclear Nickel Selenite Complex [{Ni(TMEDA)SeO3}2]"

F. Zimetti, N. Ronda, F. Bernini, E. Favari (2011) "THE NATURAL COMPOUND BERBERINE AFFECTS MACROPHAGE ABCA1 EXPRESSION AND FUNCTION TROUGH A TRANSCRIPTIONAL EFFECT "

I. Zanotti, F. Bernini (2011) "THE THIENOTRIAZOLODIAZEPINE RO 11-1464 INCREASES PLASMA APOA-I AND PROMOTES REVERSE CHOLESTEROL TRANSPORT AND FECAL STEROL EXCRETION IN HUMAN APOA-I TRANSGENIC MICE"

N. Ronda (2011) "TOLL-LIKE RECEPTOR 4 AS A CELL MEMBRANE RECEPTOR FOR BETA2 GLYCOPROTEIN I"

Marco Radi (2011) "Targeting the Human DEAD-Box Polypeptide 3 (DDX3) RNA Helicase as a Novel Strategy to Inhibit Viral Replication"

L. BATTISTINI, C. CURTI, F. ZANARDI (2011) "The Vinylogous Aldol and Related Addition Reactions:Ten Years of Progress"

P. COLOMBO (2011) "The butterfly effect: A physical phenomenon of hypromellose matrices during dissolution and the factors affecting its occurrence"

A. Mozzarelli, B. Campanini, S. Raboni (2011) "The multifaceted pyridoxal 5’-phosphate-dependent O-acetylserine sulfhydrylase"

C. Carmi, D. Pala, S. Rivara, M. Mor (2011) "Toward the Definition of Stereochemical Requirements for MT(2)-Selective Antagonists and Partial Agonists by Studying 4-Phenyl-2-propionamidotetralin Derivatives."

Marco Radi (2011) "Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation"

Pescina S, Santi P, Nicoli S (2011) "Trans-scleral delivery of macromolecules"

A. Lodola, S. Rivara, M Mor (2011) "Understanding the role of carbamate reactivity in fatty acid amide hydrolase inhibition by QM/MM mechanistic modelling. "

A. Mozzarelli (2011) "X-ray crystallography marries spectroscopy to unveil structure and function of biological macromolecules"

S. Bruno (2011) "X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: A multidisciplinary characterization of catechol 1,2 dioxygenase"

CURTI C., BATTISTINI L., ZANARDI F. (2011) "anti-Selective, Catalytic Asymmetric Vinylogous Mukaiyama Mannich Reactions of Pyrrole-Based Silyl Dienolates with N-Aryl Aldimines"