IL PORTALE per la RICERCA dei DIPARTIMENTI

Serini G. (2012) "A bistable model of cell polarity"

Marchiò S, Bussolino F (2012) "A complex of a6 integrin and E-cadherin drives the liver metastasis of colorectal cancer cells by a physical and functional interaction with hepatic angiopoietin-like 6"

Papotti M (2012) "A modified vimentin histological score helps recognize pulmonary sarcomatoid carcinoma in small biopsy samples."

F. Galimi, P. M. Comoglio, L. Trusolino*, A. Bertotti* (*Co-Senior Authors) (2012) "A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors."

Enzo Medico (2012) "ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma"

Scagliotti G (2012) "ALK translocation and crizotinib in non-small cell lung cancer: an evolving paradigm in oncology drug development."

Bardelli A (2012) "Active PI3K Pathway Causes an Invasive Phenotype Which Can Be Reversed or Promoted by Blocking the Pathway at Divergent Nodes."

Porpiglia F (2012) "Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up"

Novello S, Scagliotti G. (2012) "Aflibercept and Docetaxel Versus Docetaxel Alone After Platinum Failure in Patients With Advanced or Metastatic Non-Small-Cell Lung Cancer: A Randomized, Controlled Phase III Trial. "

REACT Study Group. (2012) "An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy."

Bo S (2012) "Anomalous thermodynamics at the microscale."

Scagliotti GV (2012) "Biomarker analysis in a phase III study of pemetrexed-carboplatin versus etoposide-carboplatin in chemonaive patients with extensive-stage small-cell lung cancer."

Scagliotti G. (2012) "Brain Metastases as the Primary Site of Relapse in Two Randomized Phase III Pemetrexed Trials in Advanced Non-Small-Cell Lung Cancer."

Di Renzo MF (2012) "Cells lacking the fumarase tumor suppressor are protected from apoptosis through a HIF-independent, AMPK dependent mechanism."

Porpiglia F (2012) "Chronic kidney disease, severe arterial and arteriolar sclerosis and kidney neoplasia: on the spectrum of kidney involvement in MELAS syndrome."

Gandolfo S, Pentenero M (2012) "Clinical and histological features of gingival lesions: A 17-year retrospective analysis in a northern Italian population"

Novello S (2012) "Clinical benefit in patients with metastatic bone disease: results of a phase 3 study of denosumab versus zoledronic acid."

Ardissone F (2012) "Colorectal cancer pulmonary oligometastases: pooled analysis and construction of a clinical lung metastasectomy prognostic model"

Levra MG (2012) "Comparison of doxorubicin and weekly paclitaxel efficacy in metastatic angiosarcomas"

Scagliotti GV (2012) "Comparison of pemetrexed plus cisplatin with other first-line doublets in advanced non-small cell lung cancer (NSCLC): A combined analysis of three phase 3 trials."

Porpiglia F (2012) "Contemporary management of ureteral stones"

Corà D (2012) "Dynamic Modeling of miRNA-mediated Feed-Forward Loops."

Riganti C (2012) "Dysfunctional V¿9Vd2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells."

Papotti M (2012) "ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Colorectal Neuroendocrine Neoplasms."

Papotti M. (2012) "ENETS Consensus Guidelines for the management of patients with liver and other distant metastases from neuroendocrine neoplasms of foregut, midgut, hindgut, and unknown primary "

Papotti M. (2012) "ENETS Consensus Guidelines for the management of patients with neuroendocrine neoplasms from the jejuno-ileum and the appendix including goblet cell carcinomas "

Misale S*, Siravegna G, Medico E, Di Nicolantonio F, Bardelli A (2012) "Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer"

Ricardi U (2012) "Epidemiology of glial and non-glial brain tumours in Europe."

Corà D (2012) "Gene autoregulation via intronic microRNAs and its functions."

Medico E (2012) "High-throughput molecular analysis from leftover of fine needle aspiration cytology of mammographically detected breast cancer."

Riganti C (2012) "Human ¿d T-cell responses in infection and immunotherapy: Common mechanisms, common mediators?"

Medico E (2012) "Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma"

Ricardi U (2012) "Incidence, survival and prevalence of myeloid malignancies in Europe."

Scagliotti GV (2012) "International, Randomized, Placebo-Controlled, Double-Blind Phase III Study of Motesanib Plus Carboplatin/Paclitaxel in Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer: MONET1"

Skorokhod O (2012) "Meeting highlights: international seminar on the red blood cells as vehicles for drugs"

F. Galimi, P. M. Comoglio, C. Boccaccio, A. Bertotti*, L. Trusolino* (*Co-Senior Authors) (2012) "Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer."

Papotti M (2012) "MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer."

Porpiglia F (2012) "Minilaparoscopy, needlescopy and microlaparoscopy: decreasing invasiveness, maintaining the standard laparoscopic approach"

Papotti M. (2012) "Multiparametric molecular characterization of pulmonary sarcomatoid carcinoma reveals a nonrandom amplification of anaplastic lymphoma kinase (ALK) gene."

Papotti M (2012) "Neuroendocrine bronchial and thymic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up"

Rizzolio S, Lanzetti L, Serini G, Tamagnone L. (2012) "Neuropilin-1 dependent regulation of EGF-Receptor signaling"

Ferru E, Giribaldi G, Turrini F (2012) "New antimalarial indolone-N-oxides, generating radical species, destabilize the host cell membrane at early stages of Plasmodium falciparum growth: role of band 3 tyrosine phosphorylation"

Battistini C (2012) "New signalling pathway involved in the antiproliferative action of Vitamin D3 and its analogues in human neuroblastoma cells. A role for ceramide kinase"

Bergandi L, Volante M, Papotti M (2012) "Obestatin regulates adipocyte function and protects against diet-induced insulin resistance and inflammation."

Scagliotti GV (2012) "Overall survival improvement in patients with lung cancer and bone metastases treated with denosumab versus zoledronic acid: subgroup analysis from a randomized phase 3 study"

Medico E (2012) "PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas."

Aglietta M (2012) "Pazopanib for metastatic soft-tissue sarcoma (PALETTE): arandomised, double-blind, placebo-controlled phase 3 trial."

Scagliotti G. (2012) "Pemetrexed Therapy in Elderly Patients With Good Performance Status: Analysis of Two Phase III Trials of Patients With Nonsquamous Non-Small-Cell Lung Cancer"

S. Doublier (2012) "Pentosan polysulfate inhibits atherosclerosis in watanabe heritable hyperlipidemic rabbits; differential modulation of metalloproteinase-2 and -9"

Tampellini M (2012) "Prediction of overall survival through circadian rest-activity monitoring during chemotherapy for metastatic colorectal cancer."

Giaj Levra M, Novello S, Scagliotti GV, Papotti M (2012) "Primary Pleuropulmonary Sarcoma: A Rare Disease Entity."

Tampellini M (2012) "Prognostic Role of Serum Parathyroid Hormone Levels in Advanced Prostate Cancer Patients Undergoing Zoledronic Acid Administration"

Scagliotti GV (2012) "Randomized phase III study of surgery alone or surgery plus preoperative cisplatin and gemcitabine in stages IB to IIIA non-small-cell lung cancer."

Ricardi U (2012) "Rare thoracic cancers, including peritoneum mesothelioma."

Scagliotti GV, Novello S (2012) "Rationale and Design of MARQUEE: A Phase III, Randomized, Double-Blind Study of Tivantinib Plus Erlotinib Versus Placebo Plus Erlotinib in Previously Treated Patients With Locally Advanced or Metastatic, Nonsquamous, Non-Small-Cell Lung Cancer."

Volante M, Rapa I, Scagliotti G, Papotti M (2012) "Ribonucleotide Reductase Large Subunit (RRM1) Gene Expression May Predict Efficacy of Adjuvant Mitotane in Adrenocortical Cancer."

E. Riccitelli (2012) "Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 ß-cell survival"

Misale S (2012) "STAT3 can serve as a hit in the process of malignant transformation of primary cells"

Capano S, Regano D, Bussolino F, Serini G (2012) "Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice"

Tampellini M (2012) "Sex moderates circadian chemotherapy effects on survival of patients with metastatic colorectal cancer: a meta-analysis."

Giordano S (2012) "Shedding-generated Met receptor fragments can be routed to either the proteasomal or the lysosomal degradation pathway."

Simona Gallo, Stefano Gatti, Tiziana Crepaldi (2012) "Signaling to cardiac hypertrophy: insights from human and mouse RASopathies"

Volante M (2012) "Somatostatin and somatostatin analogues reduce PDGF-induced endometrial cell proliferation and motility."

Medico E (2012) "Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration."

Scagliotti GV (2012) "Sunitinib Plus Erlotinib Versus Placebo Plus Erlotinib in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer: A Phase III Trial."

Massè A (2012) "Surgical hip dislocation for anatomic reorientation of slipped capital femoral epiphysis: preliminary results."

Bardelli A (2012) "Targeted therapies: how personal should we go?"

Scagliotti GV, Novello S (2012) "Tasisulam Sodium (LY573636 Sodium) as Third-Line Treatment in Patients With Unresectable, Metastatic Non-Small-Cell Lung Cancer: A Phase-II Study."

Boccaccio C. (2012) "The MET Oncogene as a Therapeutical Target in Cancer Invasive Growth"

Chiara Camillo, Letizia Lanzetti, Federico Bussolino, Guido Serini (2012) "The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling"

Elisabetta Aldieri, Elena Gazzano (2012) "The Thickness of Multi-walled Carbon Nanotubes Affects their Lung Toxicity"

Ghigo D, Riganti C (2012) "The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increases the in vitro drug delivery across blood-brain barrier cells."

Papotti M (2012) "The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group."

Bardelli A (2012) "The road to resistance: EGFR mutation and cetuximab"

Schwarzer E (2012) "The role of age and exposure to Plasmodium falciparum in the rate of acquisition of naturally acquired immunity: a randomized controlled trial."

Serini G (2012) "The vesicular SNARE Synaptobrevin is required for Semaphorin 3A axonal repulsion"

Skorokhod OA, Schwarzer E (2012) "Transfer of 4-hydroxynonenal from parasitized to non-parasitized erythrocytes in rosettes. Proposed role in severe malaria anemia"

Capparuccia L, Tamagnone L (2012) "Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform."

Di Nicolantonio F*, Bardelli A (2012) "Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR"

Scagliotti GV (2012) "Zoledronic acid in patients with stage IIIA/B NSCLC: results of a randomized, phase III study."

Papotti M. (2012) "¿Np63 (p40) and Thyroid Transcription Factor-1 Immunoreactivity on Small Biopsies or Cellblocks for Typing Non-small Cell Lung Cancer: A Novel Two-Hit, Sparing-Material Approach."