IL PORTALE per la RICERCA dei DIPARTIMENTI

Zappavigna S, Grimaldi A, Naviglio S, Caraglia M (2012) "5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress."

Altucci L (2012) "A DNA Methyltransferase Modulator Inspired by Peyssonenyne Natural Product Structures."

Botti C (2012) "A Phase II Trial of Autologous Transplantation of Bone Marrow Stem Cells For Critical Limb Ischemia: Results of N.A.P.L.E.S. Study."

Napoli C (2012) "Adult stem cells and the clinical arena: are we able to widely use this therapy in patients with chronic limbs arteriopathy and ischemic ulcers without possibility of revascularization?"

Nebbioso A, Altucci L (2012) "Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1."

Stiuso P (2012) "Antioxidant Profile and in Vitro Cardiac Radical-Scavenging versus Pro-oxidant Effects of Commercial Red Grape Juices ( Vitis vinifera L. cv. Aglianico N.). "

Banfi S (2012) "BBS1 Mutations Underlie a Wide Spectrum of Phenotypes Ranging from Nonsyndromic Retinitis Pigmentosa to Bardet-Biedl Syndrome."

Altucci L (2012) "BLUEPRINT to decode the epigenetic signature written in blood."

Lombardi A, Caraglia M (2012) "BRAF and PIK3CA genes are somatically mutated in hepatocellular carcinoma among patients from South Italy."

Altucci L (2012) "Benzodeazaoxaflavins as Sirtuin Inhibitors with Antiproliferative Properties in Cancer Stem Cells."

Brunetti G (2012) "Beyond zoster: sensory and immune changes in zoster-affected dermatomes: a review"

Oliva A (2012) "Bone marrow mesenchymal stem cell response to nano-structured oxidized and turned titanium surfaces."

Lombardi A, Caraglia M (2012) "Breast MALT lymphomas: A clinicopathological and cytogenetic study of 9 cases."

Di Domenico M (2012) "CORRELATION BETWEEN MATRIX METALLOPROTEINASE 9 AND F-18-2-FLUORO-2-DEOXYGLUCOSE-POSITRON EMISSION TOMOGRAPHY AS DIAGNOSTIC MARKERS OF LUNG CANCER"

de Nigris F, Napoli C (2012) "CXCR4 inhibitors: tumor vasculature and therapeutic challenges "

Di Domenico M (2012) "Cardiac and skeletal muscle expression of mutant beta-myosin heavy chains, degree of functional impairment and phenotypic heterogeneity in hypertrophic cardiomyopath"

Nigro V (2012) "Cardiomyopathy in patients with POMT1-related congenital and limb-girdle muscular dystrophy"

Altucci L (2012) "Carprofen analogues as sirtuin inhibitors: enzyme and cellular studies."

Colonna G (2012) "Characterization of metalloproteinases, oxidative status and inflammation levels in the different stages of fibrosis in HCV patients."

Zappavigna S, Caraglia M (2012) "Chondroitin sulphate enhances the antitumor activity of gemcitabine and mitomycin-C in bladder cancer cells with different mechanisms."

Altucci L (2012) "Chromatin accessibility, p300 and histone acetylation define PML-RARa and AML1-ETO binding sites in acute myeloid leukemia."

Botti C, Molinari A (2012) "Circulating cytokines present in the serum of peripheral arterial disease patients induce endothelial dysfunction."

Altucci L (2012) "Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues."

Caraglia M (2012) "Core-shell biodegradable nanoassemblies for the passive targeting of docetaxel: features, antiproliferative activity and in vivo toxicity. "

Banfi S (2012) "Correlation between Photoreceptor Layer Integrity and Visual Function in Patients with Stargardt Disease: Implications for Gene Therapy"

Napoli C (2012) "Current concepts in histocompatibility during heart transplant. "

Di Domenico M (2012) "Current treatment of cutaneous squamous cancer and molecular strategies for its sensitization to new target-based drugs"

Colonna G (2012) "CytokineDB and CytReD@CROM"

Di Domenico M (2012) "Cytokines and VEGF induction in orthodontic movement in animal models."

Colonna G (2012) "Cytokinome Profile of Patients with Type 2 Diabetes and/or Chronic Hepatitis C Infection"

Caraglia M (2012) "DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma. "

Abbondanza C (2012) "Decreased serum vascular endothelial growth Factor-D (VEGF-D) levels in metastatic patients with differentiated thyroid carcinoma."

Nebbioso A, Altucci L (2012) "Design, Synthesis, and Biological Evaluation of 2-Aminobenzanilide Derivatives as Potent and Selective HDAC Inhibitors."

Della Ragione F, Oliva A. (2012) "Development of innovative biopolymers and related composites for bone tissue regeneration: study of their interaction with human osteoprogenitor cells."

Giovane A, Napoli C (2012) "Different expression of CD146 in human normal and osteosarcoma cell lines."

Altucci L (2012) "Discovery of Salermide-Related Sirtuin Inhibitors: Binding Mode Studies and Antiproliferative Effects in Cancer Cells Including Cancer Stem Cells."

Napoli C (2012) "Distinct alternative splicing patterns of mediator subunit genes during endothelial progenitor cell differentiation."

Altucci L (2012) "ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia."

Caraglia M (2012) "Editorial: target therapy in brain tumours and metastases."

Quagliuolo L (2012) "Effect of Annurca Apple Polyphenols on Human HaCaT Keratinocytes Proliferation. "

Iannuzzi C (2012) "Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis"

Napoli C (2012) "Effects of intracellular acidosis on endothelial function: an overview."

Caraglia M (2012) "Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non-small lung cancer cells"

Piluso G, Nigro V. (2012) "Enhancer chip: detecting human copy number variations in regulatory elements."

Quagliuolo L (2012) "Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"

Castellano M, Caraglia M (2012) "Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid."

Giovane A, Napoli C (2012) "Evidence of Bacteroides fragilis protection from Bartonella henselae-induced damage."

Caraglia M (2012) "Exploring the efficacy and safety of single-agent sorafenib in a cohort of Italian patients with hepatocellular carcinoma. "

de Nigris F, Napoli C (2012) "Glycoxydation promotes vascular damage via MAPK-ERK/JNK pathways."

MARINO G (2012) "Growth and endothelial differentiation of adipose stem cells on polycaprolactone."

Altucci L (2012) "HDAC modulation and cell death in the clinic"

Sirangelo I (2012) "Higher susceptibility to amyloid fibril formation of the recombinant ovine prion protein modified by transglutaminase"

Capasso R, Ingrosso D (2012) "Homocysteinylated Albumin Promotes Increased Monocyte-Endothelial Cell Adhesion and Up-Regulation of MCP1, Hsp60 and ADAM17."

Ingrosso D (2012) "Hyperhomocysteinemia in chronic renal failure: alternative therapeutic strategies."

Altucci L (2012) "Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells."

Abbondanza C, Piluso G, Medici N (2012) "Identification of a functional estrogen-responsive enhancer element in the promoter 2 of PRDM2 gene in breast cancer cell lines"

Vietri MT, Cioffi M (2012) "Identification of a novel in-frame deletion in BRCA2 and analysis of variants of BRCA1/2 in Italian patients affected with hereditary breast and ovarian cancer"

BANFI S (2012) "Identification of microRNA-regulated gene networks by expression analysis of target genes."

Napoli C (2012) "Identification of valid reference housekeeping genes for gene expression analysis in tumor neovascularization studies. "

Caraglia M (2012) "Immune-modulating Effects of the Newest Cetuximab-based Chemoimmunotherapy Regimen in Advanced Colorectal Cancer Patients."

BANFI S (2012) "Impact of age at administration, lysosomal storage, and transgene regulatory elements on AAV2/8-mediated rat liver transduction"

PILUSO G (2012) "Improvement of survival in Duchenne Muscular Dystrophy: retrospective analysis of 835 patients"

Nigro V (2012) "Improving the course of muscular dystrophy?"

Quagliuolo L (2012) "In vitro model of stromal and epithelial immortalized endometriotic cells."

Benedetti R, Nebbioso A, Altucci L (2012) "Indole-derived Psammaplin A Analogs as Epigenetic Modulators With Multiple Inhibitory Activities."

Sapio L (2012) "Inorganic Phosphate as a Novel Signaling Molecule with Antiproliferative Action in MDA-MB-231 Breast Cancer Cells"

Spina A (2012) "Inorganic phosphate enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin via a p53-dependent pathway."

Colonna G (2012) "Interactomic and pharmacological insights on human sirt-1."

Balestrieri ML, Stiuso P (2012) "Interplay between membrane lipid peroxidation, transglutaminase activity and cyclooxygenase 2 expression in the tissue adjoining to breast cancer"

Caraglia M (2012) "Intrinsic resistance to selumetinib, a selective inhibitor of MEK1/2, by cAMP-dependent protein kinase A activation in human lung and colorectal cancer cells."

Ingrosso D (2012) "Low hydrogen sulphide and chronic kidney disease: a dangerous liaison."

Napoli C (2012) "Luminex and antibody detection in kidney transplantation."

Grimaldi A, Caraglia M (2012) "MOLECULAR TARGETS FOR THE TREATMENT OF MULTIPLE MYELOMA."

Napoli C (2012) "Maternal immunization affects in utero programming of insulin resistance and type 2 diabetes."

Ingrosso D (2012) "Methionine-enriched diet decreases hippocampal antioxidant defences and impairs spontaneous behaviour and long-term potentiation in rats."

Banfi S, Nigro V (2012) "Molecular diagnosis of usher syndrome: application of two different next generation sequencing-based procedures."

Altucci L (2012) "Molecular pathways: the complexity of the epigenome in cancer and recent clinical advances."

Caraglia M (2012) "Mouse models as a translational platform for the development of new therapeutic agents in multiple myeloma."

Caraglia M, Lombardi A (2012) "Nanotech revolution for the anti-cancer drug delivery through blood- brain-barrier. "

Caraglia M (2012) "Nanotechnological and biotechnological strategies for drug delivery."

Caraglia M (2012) "Nanotechnologies: a strategy to overcome blood-brain barrier."

Cacciapuoti G, Porcelli M (2012) "New determinants in the catalytic mechanism of nucleoside hydrolases from the structures of two isozymes from Sulfolobus solfataricus"

Zappavigna S, Caraglia M (2012) "New self-assembly nanoparticles and stealth liposomes for the delivery of zoledronic acid: a comparative study. "

Altucci L (2012) "New synthetic approach to paullones and characterization of their SIRT1 inhibitory activity."

Nigro V, Piluso G (2012) "Next generation sequencing (NGS) strategies for the genetic testing of myopathies"

Castoria G (2012) "Non-Steroidal Androgen Receptor Ligands: Versatile Syntheses and Biological Data."

Nebbioso A, Benedetti R, Altucci L (2012) "Nonlinear protein – nucleic acid crosslinking induced by femtosecond UV laser pulses in living cells"

Servillo L, Giovane A, Balestrieri ML (2012) "N-Methylated Tryptamine Derivatives in Citrus Genus Plants: Identification of N,N,N-Trimethyltryptamine in Bergamot"

Servillo L, Giovane A, Balestrieri ML (2012) "Occurrence of Pipecolic Acid and Pipecolic Acid Betaine (Homostachydrine) in Citrus Genus Plants"

de Nigris F (2012) "Osteosarcoma cells induce endothelial cell proliferation during neo-angiogenesis. "

Stiuso P (2012) "Oxidative Stress Effects on Endothelial Cells Treated With Different Athletes' Sera. "

MARTIN A, IANNACCONE M, GENTILE V (2012) "Pathophysiological Roles of Transglutaminase - Catalyzed Reactions in the Pathogenesis of Human Diseases"

COLONNA G (2012) "Peptide Folding Problem: A Molecular Dynamics Study on Polyalanines Using Different Force Fields."

Quagliuolo L (2012) "Peritoneal dialisi fluid activates calcium signaling and apoptosis in mesothelial cells"

Grimaldi A (2012) "Pharmacological inhibition of HSP90 and ras activity as a new strategy in the treatment of HNSCC."

Migliaccio A, Castoria G, Bilancio A (2012) "Polyproline and Tat transduction peptides in the study of the rapid actions of steroid receptors."

Napoli C (2012) "Primary prevention of atherosclerosis: a clinical challenge for the reversal of epigenetic mechanisms? "

Di Domenico M (2012) "Proteomics in Meniere disease"

Lombardi A, Caraglia M (2012) "Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases."

BONTEMPO P, BENEDETTI R, NEBBIOSO A, CIOFFI M, ALTUCCI L (2012) "Psidium guajava L. anti-neoplastic effects: induction of apoptosis and cell differentiation"

Zappavigna S, Caraglia M (2012) "Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells. "

Nebbioso A (2012) "Rarity of human T helper 17 cells is due to retinoic acid orphan receptor-dependent mechanisms that limit their expansion."

Iannuzzi C, Irace G, Sirangelo I (2012) "Resolution of the effects induced by W ¿ F substitutions on the conformation and dynamics of the amyloid-forming apomyoglobin mutant W7FW14F."

Cacciapuoti G, Porcelli M (2012) "Role of disulfide bonds in conformational stability and folding of 5'-deoxy-5'-methylthioadenosine phosphorylase II from the hyperthermophilic archaeon Sulfolobus solfataricus"

Stiuso P, Caraglia M (2012) "Role of endothelial nitric oxide synthase (eNOS) in chronic stress-promoted tumour growth. "

Ingrosso D (2012) "Role of folic acid depletion on homocysteine serum level in children and adolescents with epilepsy and different MTHFR C677T genotypes."

Caraglia M (2012) "Role of systemic chemotherapy in the management of resected or resectable colorectal liver metastases: a systematic review and meta-analysis of randomized controlled trials. "

Nebbioso A, Altucci L (2012) "Sirtuins and disease: the road ahead."

Porcelli M, Cacciapuoti G (2012) "Site-directed mutagenesis gives insights into substrate specificity of Sulfolobus solfataricus purine-specific nucleoside hydrolase"

Napoli C (2012) "Six-minute walking test but not ejection fraction predicts mortality in elderly patients undergoing cardiac rehabilitation following coronary artery bypass grafting "

Caraglia M (2012) "Synthetic miR-34a mimics as a novel therapeutic agent for Multiple Myeloma: in vitro and in vivo evidence."

Migliaccio A, Castoria G (2012) "Targeting rapid action of sex-steroid receptors in breast and prostate cancers. "

Colonna G (2012) "The N-terminal Region of CXCL11 as Structural Template for CXCR3 Molecular Recognition: Synthesis, Conformational Analysis, and Binding Studies."

Zappavigna S, Caraglia M (2012) "The PPAR-¿ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-ß treated pancreatic cancer cells. "

Di Domenico M (2012) "The Role of Chlamydia and Chlamydophila Infections in Reactive Arthritis"

Banfi S (2012) "The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy."

Irace G, Sirangelo I (2012) "The effect of heparin on amyloid aggregation and toxicity"

Banfi S (2012) "The long non-coding RNA Vax2os1 controls the cell cycle progression of photoreceptor progenitors in the mouse retina"

NEBBIOSO A, ALTUCCI L (2012) "The new low-toxic histone deacetylase inhibitor S-(2) induces apoptosis in various acute myeloid leukemia cells"

Di Domenico M (2012) "The p85a regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration."

MANNA C (2012) "The role of iron toxicity in oxidative stress-induced cellular degeneration in Down Syndrome: protective effects of phenolic antioxidants."

Di Domenico m (2012) "The value of matrix metalloproteinase-9 and vascular endothelial growth factor receptor 1 pathway in diagnosing indeterminate pleural effusion"

Ingrosso D (2012) "Therapy of Hyperhomocysteinemia in Hemodialysis Patients: Effects of Folates and N-Acetylcysteine."

Porcelli M, Cacciapuoti G (2012) "Thermal unfolding of nucleoside hydrolases from the hyperthermophilic Archaeon Sulfolobus solfataricus: role of disulfide bonds"

Balestrieri ML, Stiuso P (2012) "Tight glycemic control may increase regenerative potential of myocardium during acute infarction. "

Iannaccone M, Antonio Martin, Vittorio Gentile (2012) "Transglutaminase inhibition: A therapy to protect cells from death in neurodegeneration?"

Nebbioso A, Benedetti R, Altucci L (2012) "Trials with 'epigenetic' drugs: An update."

Caraglia M (2012) "Tumour-specific uptake of anti-cancer drugs: the future is here. "

Castoria G, de Falco A, Abbondanza C, Migliaccio A (2012) "Tyrosine phosphorylation of estradiol receptor by Src regulates its hormone-dependent nuclear export and cell cycle progression in breast cancer cells. "

Nebbioso A, Altucci L (2012) "UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression."

Napoli C (2012) "Unraveling framework of the ancestral Mediator complex in human diseases."

Sapio L, Chiosi E, Naviglio S. (2012) "cAMP elevation down-regulates beta3 integrin and Focal Adhesion Kinase and inhibits leptin-induced migration of MDA-MB-231 breast cancer cells"

Caraglia M (2012) "miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1. "

Altucci L (2012) "miRNA-mediated deregulation in leukemia."

Grimaldi A, Caraglia M, Di Domenico M. (2012) "pEGFR-Tyr 845 expression as prognostic factors in oral squamous cell carcinoma: A tissue-microarray study with clinic-pathological correlations."