IL PORTALE per la RICERCA dei DIPARTIMENTI

Tintori C, Botta M (2012) "'Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells."

Dreassi E., Botta M. (2012) "A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model:from in silico screening to cyclodextrin formulation"

F. MANETTI, Taddei M (2012) "Acylthiourea, Acylurea and Acylguanidine Derivatives with potent Hedgehog inhibiting Activity"

Maurizio Botta (2012) "Antitumor activity of new pyrazolo[3,4-d]pyrimidine SRC kinase inhibitors in Burkitt lymphoma cell lines and its enhancement by WEE1 inhibition"

S. A. Loiselle (2012) "Basin-scale Control on the Phytoplankton Biomass in Lake Victoria, Africa"

SINICROPI A. (2012) "Bathochromic shift in Green Fluorescent Protein: A puzzle for QM/MM approaches"

Gaggelli E, Valensin G (2012) "Capreomycin - A polypeptide antitubercular antibiotic with unusual binding properties toward copper(II)"

Steven Loiselle, Claudio Rossi (2012) "Chemical and optical phototransformation of dissolved organic matter"

Mugnaini C., Corelli F. (2012) "Comparison of the effect of the positive allosteric modulator of the GABAb receptor, GS39783, on alcohol self-administration in three different lines of alcohol-preferring rats"

Daniela Valensin (2012) "Coordination of Ni2+ and Cu2+ to metal ion binding domains of E. coli SlyD protein"

Valensin D. (2012) "Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)"

Brindisi M (2012) "Developing ß-secretase inhibitors for treatment of Alzheimer’s disease"

Tintori C, Botta M (2012) "Development of an AlphaScreen-Based HIV-1 Integrase Dimerization Assay for Discovery of Novel Allosteric Inhibitors."

Tintori C, Botta M. (2012) "Discovery of small molecule HIV-1 integrase dimerization inhibitors."

Massimo Olivucci (2012) "Dynamic Electron Correlation Effects on the Ground State Potential Energy Surface of a Retinal Chromophore Model"

Giorgi G. (2012) "Gas-phase doubly charged complexes of cyclic peptides with copper in +1, +2 and +3 formal oxidation states: formation, structures and electron capture dissociation"

Tintori C., Botta M. (2012) "Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling."

Baratto M.C., Basosi R. (2012) "Influence of pH on the speciation of copper(II) in reactions with the green tea polyphenols, epigallocatechin gallate and gallic acid"

Mugnaini C., Brizzi A., Corelli F. (2012) "Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 6. Synthesis and Pharmacological Evaluation of 7-Substituted 4-Quinolone-3-carboxamide Derivatives as High Affinity Ligands for Cannabinoid Receptors"

Mugnaini C., Tafi A., Corelli F. (2012) "Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach."

Fusi S., Olivucci M. (2012) "Mechanistic Origin of the Vibrational Coherence Accompanying the Photoreaction of Biomimetic Molecular Switches"

Claudia Bonechi (2012) "Methyl carnosate, an antibacterial diterpene isolated from Salvia officinalis leaves"

Sandra Gemma, Margherita Brindisi, Simone Brogi, Stefania Lamponi, Luisa Savini, Giuseppe Campiani, Stefania Butini (2012) "Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents"

F. MANETTI, Botta M (2012) "MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212"

Niccolai N. (2012) "NMR Studies on Structure and Dynamics of the Monomeric Derivative of BS-RNase: New Insights for 3D Domain Swapping."

Valensin D., Gaggelli E., Valensin G. (2012) "NMR metabolomic investigation of astrocytes interacted with Aß42 or its complexes with either copper(II) or zinc(II)"

Botta M (2012) "New pyrazolo[3,4-d]pyrimidine SRC inhibitors induce apoptosis in mesothelioma cell lines through p27 nuclear stabilization."

Loiselle Steven Arthur (2012) "Optical approaches to examining the dynamics of dissolved organic carbon in optically complex inland waters"

Sandra Gemma, Simone Brogi, Luisa Savini, Stefania Lamponi, Giuseppe Campiani, Stefania Butini (2012) "Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling"

Massimo Olivucci (2012) "Origin of Fluorescence in 11-cisLocked Bovine Rhodopsin"

Stefania Fusi, Massimo Olivucci (2012) "Photoisomerization and Relaxation Dynamics of a Structurally Modified Biomimetic Photoswitch"

Massimo Olivucci (2012) "Quantum chemical modeling of rhodopsin mutants displaying switchable colors"

Sandra Gemma, Margherita Brindisi, Simone Brogi, Luisa Savini, Stefania Butini, Giuseppe Campiani (2012) "Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1"

Trabalzini L (2012) "Reactive oxygen species: friends and foes of signal transduction."

Marco Paolino, Andrea Cappelli (2012) "Self-assembly of poly(propylene imine) glycodendrimers: role of aromatic interactions in the formation of necklace- and donut-like nanostructures"

Valensin G (2012) "Specific poly-histidyl and poly-cysteil protein sites involved in Ni(2+) homeostasis in Helicobacter pylori. Impact of Bi(3+) ions on Ni(2+) binding to proteins. Structural and thermodynamic aspects"

Cini E (2012) "Stereoarrays with an All-Carbon Quaternary Center: Diasteroselective Desymmetrization of Prochiral Malonaldehydes"

Taddei M. (2012) "Stereoselective multicomponent assembly of enantiopure oxazolopiperidines and –azepines"

S. Mangani, C. Pozzi (2012) "Structural Insights into the Ferroxidase Site of Ferritins from Higher Eukaryotes"

D. VALENSIN (2012) "Structural characterization of Cu2+, Ni2+ and Zn2+ binding sites of model peptides associated with neurodegenerative diseases"

Dreassi E, Botta M. (2012) "Synthesis, biological activity, and ADME properties of novel S-DABOs/N-DABOs as HIV reverse transcriptase inhibitors."

Maccari G., Botta M. (2012) "Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin A-1."

Massimo Olivucci (2012) "The Molecular Mechanism of Dark Noise in Rod Photoreceptors"

Pozzi C, Mangani S (2012) "The structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism."

Spiga O., Botta M., Niccolai N. (2012) "The use of a ditopic Gd(III) paramagnetic probe for investigating a-bungarotoxin surface accessibility."

Valensin D. (2012) "Thermodynamic and spectroscopic investigation on the role of Met residues in Cu II binding to the non-octarepeat site of the human prion protein"

Botta M. (2012) "Use of virtual screening for discovering antiretroviral compounds interacting with the HIV-1 nucleocapsid protein."

Claudia Bonechi, Stefania Lamponi, Claudio Rossi (2012) "Using Liposomes as Carriers for Polyphenolic Compounds: The Case of Trans-Resveratrol"

Manetti F., Botta M. (2012) "Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach"