IL PORTALE per la RICERCA dei DIPARTIMENTI

Laura Di Francesco, Bruno Maras, Maria Eugenia Schinina' (2012) "14-3-3e marks the amyloid-stimulated microglia long-term activation"

Marzia Perluigi, Raffaella Coccia (2012) "4-Hydroxy-2-Nonenal, a Reactive Product of Lipid Peroxidation, and Neurodegenerative Diseases: A Toxic Combination Illuminated by Redox Proteomics Studies"

Gianni S (2012) "A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein."

Boffi A (2012) "A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition."

E. AGOSTINELLI (2012) "A rapid and robust assay for the determination of the amino acid hypusine as a possible biomarker for a high-throughput screening of antimalarials and for the diagnosis and therapy of different diseases."

A. Macone, R.M. Matarese (2012) "Absorption of aminoethylcysteine ketimine decarboxylated dimer in mice. "

Maria Eugenia Schinina' (2012) "Acetylation controls Notch3 stability and function in T-cell leukemia"

Gianni S (2012) "An expanded view of the protein folding landscape of PDZ domains."

Fabio Di Domenico, Raffaella Coccia, Marzia Perluigi (2012) "Antioxidants in cervical cancer: Chemopreventive and chemotherapeutic effects of polyphenols"

Olfa Tabbene & Dorra Gharbi & Imen Ben Slimene & Salem Elkahoui & Mohamed Najib Alfeddy & Pascal Cosette & Maria Luisa Mangoni & Thierry Jouenne & Ferid Limam (2012) "Antioxidative and DNA Protective Effects of Bacillomycin D-Like Lipopeptides Produced by B38 Strain"

Di Domenico F (2012) "Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain."

Fabio Di Domenico (2012) "Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease"

DI SALVO ML, CONTESTABILE R. (2012) "Biomedical aspects of pyridoxal 5’-phosphate availability"

Mosca L (2012) "Bone tissue: hormonal regulating systems, growth factors and remodelling as a target for therapeutic agents in oteoporosis"

Laura Politi (2012) "Cadmium-induced apoptosis and necrosis in human osteoblasts: Role of caspases and mitogen-activated protein kinases pathways"

M. Eugenia Schininà, Bruno Maras (2012) "Calcium Binding Promotes Prion Protein Fragment 90–231 Conformational Change toward a Membrane Destabilizing and Cytotoxic Structure"

Fabio Altieri (2012) "Calcium carbonate mineralization: Involvement of extracellular polymeric materials isolated from calcifying bacteria"

Alberto Boffi (2012) "Carbon Monoxide Recombination Dynamics in Truncated Hemoglobins Studied with Visible-Pump MidIR-Probe Spectroscopy"

Enzo Agostinelli (2012) "Catalytically active bovine serum amine oxidase bound to fluorescent and magnetically drivable nanoparticles"

M. Perluigi (2012) "Cell Cycle Proteins in Brain in Mild Cognitive Impairment: Insights into Progression to Alzheimer Disease."

Agostinelli Enzo (2012) "Chronic exposure to agmatine results in the selection of agmatine-resistant hepatoma cells."

Martino Luigi Di Salvo, Roberto Contestabile (2012) "Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition"

Giorgio Giardina, Andrea Bellelli, Adriana Erica Miele (2012) "Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target"

Maria Carmela Bonaccorsi di Patti, Laura Cervoni, M. Eugenia Schinina` (2012) "Cupricyclins, novel redox-active metallopeptides based on conotoxins scaffold."

Paolo Sarti, Elena Forte (2012) "Cytochrome bd oxidase and nitric oxide: From reaction mechanisms to bacterial physiology"

Paolo Sarti, Elena Forte, Marzia Arese (2012) "Cytochrome c oxidase and nitric oxide in action: Molecular mechanisms and pathophysiological implications"

Fabio Di Domenico, Raffaella Coccia, Marzia Perluigi (2012) "Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics"

L. di Francesco, M.E. Schininà (2012) "Differential phosphoproteome analysis of K562 cells exposed to 3'-Azido- 3'-Deoxythymidine (AZT)."

Enzo Agostinelli (2012) "Do mammalian amine oxidases and the mitochondrial polyamine transporter have similar protein structures?"

Fabio Altieri (2012) "Dystroglycan is associated to the disulfide isomerase ERp57"

Tempera G, Agostinelli E (2012) "Effect of peroxides on spermine transport in rat brain and liver mitochondria"

Luciana Mosca (2012) "Effects of methanolic extract of sour cherry (Prunus cerasus L.) on microbial growth"

Paone A (2012) "Epigenetic Regulation of miRNAs in Cancer."

Sarti P (2012) "Experimental teaching program on cooperation between "Sapienza" University of Rome and the University Hospital "Le Bon Samaritain" in N'Djamena, Chad]"

Travaglini-Allocatelli C, Gianni S (2012) "Folding pathways of proteins with increasing degree of sequence identities but different structure and function"

Bonamore A, Boffi A (2012) "Following ligand migration pathways from picoseconds to milliseconds in type II truncated hemoglobin from Thermobifida fusca."

Enzo Agostinelli (2012) "Further characterization of agmatine binding to mitochondrial membranes: involvement of imidazoline I2 receptor "

Gianni S (2012) "GA/GB fold switching may modulate fatty acid transfer from human serum albumin to bacteria."

Maria Eugenia Schinina' (2012) "HIPK2 Controls Cytokinesis and Prevents Tetraploidization by Phosphorylating Histone H2B at the Midbody"

Fabio Di Domenico, Marzia Perluigi, Raffaella Coccia (2012) "HO-1/BVR-A system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: A potential biochemical marker for the prediction of the disease"

Fabio Di Domenico, Raffaella Coccia, Marzia Perluigi (2012) "Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment"

Anna Scotto D'Abusco (2012) "Hypogonadism in a patient with two novel mutations of the luteinizing hormone ß-subunit gene expressed in a compound heterozygous form."

Alessandro Paiardini (2012) "Identification by Virtual Screening and In Vitro Testing of Human DOPA Decarboxylase Inhibitors"

Laura Di Francesco, Maria Eugenia Schininà (2012) "Importin-ß negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores"

Mosca L, Chiaraluce R, Consalvi V (2012) "Inhibition of amyloid peptide fragment Aß25-35 fibrillogenesis and toxicity by N-terminal ß-amino acid-containing esapeptides: is taurine moiety essential for in vivo effects?"

Fabio Di Domenico, Marzia Perluigi (2012) "Inhibition of lipid peroxidation and protein oxidation by endogenous and exogenous antioxidants in rat brain microsomes in vitro"

Maria Rosaria Fullone, Alessandro Paiardini, Rossella Miele, Maria Carmela Bonaccorsi Di Patti, Stefano Pascarella, Ingeborg Grgurina (2012) "Insight into the structure-function relationship of the nonheme iron halogenases involved in the biosynthesis of 4-chlorothreonine-Thr3 from Streptomyces sp OH-5093 and SyrB2 from Pseudomonas syringae pv. syringae B301DR"

Silvia Chichiarelli, Caterina Grillo, Fabio Altieri (2012) "Interaction of ERp57 with calreticulin: Analysis of complex formation and effects of vancomycin"

E. AGOSTINELLI (2012) "Interactions of melatonin with mammalian mitochondria. Reducer of energy capacity and amplifier of permeability transition."

Serena Rinaldo, Francesca Cutruzzola', Stefano Gianni (2012) "Interactions outside the Boundaries of the Canonical Binding Groove of a PDZ Domain Influence Ligand Binding"

Maria Luisa Mangoni (2012) "Isomerization of an Antimicrobial Peptide Broadens Antimicrobial Spectrum to Gram-Positive Bacterial Pathogens"

L. Politi, A. Scotto d'Abusco (2012) "L-Carnitine enhances extracellular matrix synthesis in human primary chondrocytes"

Fabio Di Domenico, Marzia Perluigi (2012) "Lack of p53 Decreases Basal Oxidative Stress Levels in the Brain Through Upregulation of Thioredoxin-1, Biliverdin Reductase-A, Manganese Superoxide Dismutase, and Nuclear Factor Kappa-B"

Paola Pietrangeli, Andrea Bellelli (2012) "Lathyrus cicera copper amine oxidase reactions with tryptamine"

Gianni S (2012) "Ligand binding by PDZ domains."

Paone A (2012) "MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response."

Enzo Agostinelli (2012) "Mitochondrial oxidative stress induced by Ca 2+ and monoamines: Different behaviour of liver and brain mitochondria in undergoing permeability transition"

Alessandro Paiardini (2012) "Molecular insights into primary hyperoxaluria type i pathogenesis"

Patrizio Di Micco, Adriana Erica Miele, Andrea Bellelli (2012) "Moonlighting by Different Stressors: Crystal Structure of the Chaperone Species of a 2-Cys Peroxiredoxin"

Stefano Gianni, Carlo Travaglini Allocatelli (2012) "Morphogenesis of a protein: folding pathways and the energy landscape"

Marzia Arese, Fabio Altieri, Caterina Grillo, Paolo Sarti (2012) "Nanomolar melatonin enhances nNOS expression and controls HaCaT-cells bioenergetics"

Andrea Bellelli, Elena Forte (2012) "Nitric oxide, substrate of Euphorbia characias peroxidase, switches off the CN- inhibitory effect"

Serena Rinaldo, Giorgio Giardina, Francesca Cutruzzola' (2012) "Nitrite and Nitrite Reductases: From Molecular Mechanisms to Significance in Human Health and Disease"

Adriana Erica Miele, Andrea Bellelli (2012) "On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases"

Carla Blarzino, Maria Eugenia Schinina', Fabio Di Domenico, Raffaella Coccia, Marzia Perluigi (2012) "Oxidative Stress in HPV-Driven Viral Carcinogenesis: Redox Proteomics Analysis of HPV-16 Dysplastic and Neoplastic Tissues"

Elisabetta Capuozzo, Mario Fontana (2012) "Oxidative and nitrative modifications of enkephalins by human neutrophils: effect of nitroenkephalin on leukocyte functional responses"

Marzia Perluigi (2012) "Oxidative stress and down syndrome: A route toward Alzheimer-like dementia"

Giampiero Tempera, Enzo Agostinelli (2012) "Polyamine catabolism: target for antiproliferative therapies in animals and stress tolerance strategies in plants"

Marcocci L (2012) "Proposed role of primary protein carbonylation in cell signaling"

Emanuele Bramucci, Alessandro Paiardini, Stefano Pascarella (2012) "PyMod: sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL"

Roberto Contestabile, Martino L. di Salvo, Alessia Parroni (2012) "Pyridoxal 5’-Phosphate is a Slow Tight Binding Inhibitor of E. coli Pyridoxal Kinase"

Alessandro Paiardini (2012) "Rapid profiling of disease alleles using a tunable reporter of protein misfolding"

Gianni S. (2012) "Reassessing the folding of the KIX domain: evidence for a two-state mechanism."

Fabio Di Domenico, Marzia Perluigi, Raffaella Coccia (2012) "Redox Proteomics Analyses of the Influence of Co-Expression of Wild-Type or Mutated LRRK2 and Tau on C. elegans Protein Expression and Oxidative Modification: Relevance to Parkinson Disease"

Marzia Perluigi (2012) "Redox Proteomics in Selected Neurodegenerative Disorders: From Its Infancy to Future Applications"

Agostinelli E. (2012) "Role of polyamines, their analogs and transglutaminases in biological and clinical perspectives. "

Silvia Chichiarelli (2012) "Self-assembled gellan-based nanohydrogels as a tool for prednisolone delivery"

Sebastiana Angelaccio, Valerio Consalvi, Stefano Pascarella (2012) "Serine Hydroxymethyltransferase from the Cold Adapted Microorganism Psychromonas ingrahamii: A Low Temperature Active Enzyme with Broad Substrate Specificity"

Fabio Di Domenico, Marzia Perluigi, Maria Eugenia Schinina', Carla Blarzino, Raffaella Coccia (2012) "Serum proteomics in patients with diagnosis of abdominal aortic aneurysm"

F. Di Domenico, C. Cini, M. Perluigi (2012) "Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion."

Gianni S (2012) "Side-Chain Interactions Form Late and Cooperatively in the Binding Reaction between Disordered Peptides and PDZ Domains."

Rinaldo S, Cutruzzolà F (2012) "Solvent Accessibility in the Distal Heme Pocket of the Nitrosyl d1-Heme Complex of Pseudomonas Stutzeri cd1 Nitrite Reductase."

V. Consalvi, R. Chiaraluce (2012) "Structural stability of human protein tyrosine phosphatase catalytic domain: effect of point mutations"

F. Altieri, L. Cervoni (2012) "Synthesis, Characterization and Biological Evaluation of Ureidofibrate-Like Derivatives Endowed with Peroxisome Proliferator-Activated Receptor Activity"

Beatrice Vallone (2012) "The Monod-Wyman-Changeux allosteric model accounts for the quaternary transition dynamics in wild type and a recombinant mutant human hemoglobin"

Carlotta Zamparelli (2012) "The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase"

Paolo Sarti, Elena Forte, Marzia Arese (2012) "The chemical interplay between nitric oxide and mitochondrial cytochrome c oxidase: Reactions, effectors and pathophysiology"

Boffi A (2012) "The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway."

Gianni S (2012) "Tolerance of protein folding to a circular permutation in a PDZ domain."

Giuseppina Mignogna, Maria L. Mangoni (2012) "Towards an improved structural model of the frog-skin antimicrobial peptide esculentin-1b(1-18)"

Luciana Mosca, Maria D'Erme, Antonio Francioso (2012) "Transient increase in neuronal chloride concentration by neuroactive amino acids released from glioma cells"

Serena Rinaldo, Giorgio Giardina, Francesca Cutruzzola' (2012) "Unusual Heme Binding Properties of the Dissimilative Nitrate Respiration Regulator, a Bacterial Nitric Oxide Sensor"

Paone A (2012) "miR-EdiTar: a database of predicted A-to-I edited miRNA target sites."

Paone A (2012) "rs4919510 in hsa-mir-608 is associated with outcome but not risk of colorectal cancer."