IL PORTALE per la RICERCA dei DIPARTIMENTI

Cosimelli B., Di Maro S., Marinelli L., Greco G., Novellino E. (2012) "3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists"

S. De Marino, M. V. D’Auria, A. Zampella (2012) "4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity"

C. Irace (2012) "A Cholesterol-based Nucleolipid-Ruthenium complex stabilized bylipid aggregates for antineoplastic therapy"

Marinelli L (2012) "A Conformationally Frozen Peptoid Boosts CXCR4 Affinity and Anti-HIV Activity."

Giorgia Oliviero, Nicola Borbone, Luciano Mayol, Gennaro Piccialli (2012) "A Facile Synthesis of 5'-Fluoro-5'-deoxyacadesine (5'-F-AICAR): A Novel Non-phosphorylable AICAR Analogue"

S. Albrizio (2012) "A GC–FID Method to Determine Styrene in Polystyrene Glasses"

Serenella Seccia, Stefania Albrizio (2012) "A Simple and Selective Analytical Procedure for the Extraction and Quantification of Lutein from Tomato By-Products by HPLC-DAD"

Miniaci MC (2012) "A cellular model of memory reconsolidation involves reactivation-induced destabilization and restabilization at the sensorimotor synapse in Aplysia."

Pennacchio A (2012) "A new competitive fluorescence immunoassay for detection of Listeria monocytogenes"

Grassia G, Maffia P (2012) "A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo."

Romanelli A. (2012) "A novel synthetic peptide from a tomato defensin exhibits antibacterial activities against Helicobacter pylori"

De Napoli L. (2012) "A novel synthetic strategy for mono-substituted cyclodextrin derivatives"

S. Galdiero (2012) "A viral peptide for intracellular delivery"

Cosimelli B. (2012) "Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects"

Marasco D (2012) "Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers"

S. Galdiero, G. Morelli, D. Tesauro (2012) "Activation of monocytic cells by immunostimulatory lipids conjugated to peptide antigens"

PAGANO D (2012) "An efficient and versatile chemical synthesis of bioactive glyco-glycerolipids"

C. Formisano, D. Rigano, F. Senatore (2012) "Anthemis wiedemanniana essential oil prevents LPS-induced production of NO in RAW 264.7 macrophages and exerts antiproliferative and antibacterial activities in vitro"

C. Festa, S. De Marino, M. V. D’Auria, M. Bucci, V. Vellecco, A. Zampella (2012) "Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei"

Novellino E. (2012) "Antifungal peptides at membrane interaction."

S. De Marino, C. Festa, F. Zollo (2012) "Antioxidant activity of phenolic and phenylethanoid glycosides from Teucrium polium L"

Ritieni A. (2012) "Antioxidant activity of some medicinal and dietary African vegetables"

G. C. TENORE, I. M. G. MONTERREY (2012) "Antioxidant profile and in vitro cardiac radical-scavenging versuspro-oxidant effects of commercial red grape juices (Vitis vinifera L.cv. Aglianico N.)"

A. Aiello, C. Imperatore, M. Menna (2012) "Aplisulfamines, New Sulfoxide-Containing Metabolites from an Aplidium Tunicate: Absolute Stereochemistry at Chiral Sulfur and Carbon Atoms Assigned Through an Original Combination of Spectroscopic and Computational Methods"

Bucci M, Vellecco V, Rossi A, Sautebin L, Ianaro A, Cirino G. (2012) "Apolipoprotein A-I (ApoA-I) Mimetic Peptide P2a by Restoring CholesterolEsterification Unmasks ApoA-I Anti-Inflammatory Endogenous Activity In Vivo."

Ritieni A. (2012) "Arterial Cord Blood Lutein Levels in Preterm and Term Healthy Newborns are sex and Gestational Age Dependent"

M.C. Maiuri (2012) "Autophagy is required for the activation of NF¿B."

Perrone-Capano C. (2012) "Balance between excitation and inhibition controls the temporal organization of neuronal avalanches."

S Di Maro, E Novellino (2012) "Benzodeazaoxaflavins as Sirtuin Inhibitors with Antiproliferative Properties in Cancer Stem Cells"

L Marinelli, S Di Maro, E Novellino (2012) "Benzofuroxane Derivatives as Multi-Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies"

Santini A., Ritieni A. (2012) "Berries contamination by microfungi in Slovakia vineyards regions: impact of climate conditions on microfungi biodiversity"

GRASSIA G., CICALA C., IUVONE T., MAFFIA P., MASCOLO N., IALENTI A. (2012) "Bindarit inhibits human coronary smooth muscle cell proliferation, migration and phenotypic switching."

Ritieni A. (2012) "Bioaccessibility of Deoxynivalenol and its natural co-occurrence, with Ochratoxin A and Aflatoxin B1 in italian commercial pasta"

P. Ciminiello, C. Dell’Aversano, L. Tartaglione (2012) "Biogeographic effects of the Gulf of Mexico red tide dinoflagellate Karenia brevis on Mediterranean copepods"

Galdiero S. (2012) "Biophysical characterization and membrane interaction of the two fusion loops of glycoprotein B from herpes simplex type I virus."

Valeria Costantino, Alfonso Mangoni, Roberta Teta (2012) "Blurring the Boundary between Bio- and Geohopanoids: Plakohopanoid, a C32-Biohopanoid Ester from Plakortis cf. lita"

A Accardo, G. Salzano, C. Cicala, D. Tesauro, G. De Rosa, G. Morelli (2012) "Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells"

De Cicco P (2012) "Butyrate attenuates lipopolysaccharide-induced inflammation in intestinal cells and Crohn's mucosa through modulation of antioxidant defense machinery."

Lavecchia A., Novellino E. (2012) "CDC25 Phosphatase Inhibitors: An Update"

M. C. Maiuri, R. Carnuccio (2012) "Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines."

Izzo A.A. (2012) "Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation."

E Novellino (2012) "Carprofen Analogues as Sirtuin Inhibitors: Enzyme and Cellular Studies"

Russo R, Mattace Raso G, Avagliano C, Meli R, Calignano A. (2012) "Central administration of oxytocin reduces hyperalgesia in mice: Implication for cannabinoid and opioid systems."

Roberta Teta, Alfonso Mangoni, Valeria Costantino (2012) "Chalinulasterol, a Chlorinated Steroid Disulfate from the Caribbean Sponge Chalinula molitba. Evaluation of Its Role as PXR Receptor Modulator"

Ritieni A. (2012) "Characterization of Heat-Labile toxin-subunit B from Escherichia coli by liquid chromatography-electrospray ionization-mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry"

Carmen Festa, Angela Zampella (2012) "Chemical Proteomics Reveals Heat Shock Protein 60 To Be the Main Cellular Target of the Marine Bioactive Sesterterpene Suvanine"

F. Senatore (2012) "Chemical composition of essential oil from Italian populations of Artemisia alba Turra (Asteraceae)"

C. Formisano, D. Rigano, F. Senatore (2012) "Chemical composition of the essential oil of Teucrium flavum ssp. flavum from Zakynthos, Greece."

C. Formisano, F. Senatore (2012) "Chemical composition of the essential oils of Centaurea formanekii Halacsy and Centaurea orphanidea Heldr. & Sart. ex Boiss. ssp. thessala (Hausskn.) Dostál, two Centaurea species growing wild in Greece."

Tenore G.C., Novellino E. (2012) "Chemical composition, antioxidant and antimicrobial properties of Rapa Catozza Napoletana (Brassica rapa L. var. rapa DC.) seed meal, a promising protein source of Campania region (southern Italy) horticultural germplasm."

PAGANO D (2012) "Chemo-enzymatic preparation of alpha-6-sulfoquinovosyl-1,2-O-diacylglycerols"

B. Romano, F. Borrelli, R. Capasso, A. A. Izzo (2012) "Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer."

Grieco P. (2012) "Chondroprotective and Anti-Inflammatory role of Melanocortin peptides in TNF-a activated human C-20/A4 chondrocytes."

A. SANTINI (2012) "Comparison of frying performance of olive oil, bi-fractionated palm oil and sunflower oil"

Borrelli F (2012) "Complementary and alternative medicine and cancer survivorship."

Lavecchia A. (2012) "Conformational switch of a flexible loop in human laminin receptor determines laminin-1 interaction"

Sepe V., D'Auria M. V., Zampella A. (2012) "Conicasterol E, a Small Heterodimer Partner Sparing Farnesoid X Receptor Modulator Endowed with a Pregnane X Receptor Agonistic Activity, from the Marine Sponge Theonella swinhoei"

E Menditto (2012) "Consumption of biosimilar drugs in Campania Region for the years 2008-2011"

F. Ungaro, G. Misso, F. Quaglia (2012) "Core-shell biodegradable nanoassemblies for the passive targeting of docetaxel: features, antiproliferative activity and in vivo toxicity"

Bruno A (2012) "Crosstalk within GPCR Heteromers in Schizophrenia and Parkinson's Disease: Physical or Just Functional?"

L.Ferrara (2012) "Cytological Aspects on the Effects of a Nasal Spray Consisting of Standardized Extract of Citrus Lemon and Essential Oils in Allergic Rhinopathy"

G. Mattace Raso, R. Meli (2012) "Deletion of prolyl carboxypeptidase attenuates the metabolic effects ofdiet-induced obesity"

Galdiero S. (2012) "Dendrimer functionalization with a membrane-interacting domain of herpes simplex virus type 1: towards intracellular delivery."

A. Bruno (2012) "Design and synthesis of trans-2-substituted-cyclopropane-1-carboxylic acids as the first non-natural small molecule inhibitors of O-acetylserine sulfhydrylase"

Carotenuto A., Novellino E. (2012) "Designed glucopeptides mimetics of myelin protein epitopes as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis"

Maffia P (2012) "Detection of inflammation in vivo by surface-enhanced Raman scattering provides higher sensitivity than conventional fluorescence imaging"

L. Ferrara, A. Santini (2012) "Determination of cholesterol in italian chicken eggs"

Ritieni A. and Mañes J. (2012) "Determination of trichothecenes and zearalenones in grain cereal, flour and bread by liquid chromatography tandem mass spectrometry"

A. Zampella (2012) "Development of FXR, PXR and CAR agonists and antagonists for treatment of liver disorders"

Alfonso Mangoni, Valeria Costantino (2012) "Development of a fluorescent probe for the study of the sponge-derived simplexide immunological properties"

Lavecchia A., Novellino E. (2012) "Diarylheterocycle Core Ring Features Effect in Selective COX-1 Inhibition"

Ritieni A. (2012) "Dietary approach in the prevention and treatment of NAFLD"

Maiuri M.C. (2012) "Direct molecular interactions between Beclin 1 and the canonical NF¿B activation pathway."

Volpicelli F, De Gregorio R (2012) "Direct regulation of Pitx3 expression by Nurr1 in culture and in developing mouse midbrain."

Lavecchia A., Novellino E. (2012) "Discovery of New Inhibitors of Cdc25B Dual Specificity Phosphatases by Structure-Based Virtual Screening"

D'Auria M.V., Sepe V., Zampella A. (2012) "Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis"

Cicala C., Mascolo N. (2012) "Diuretic activity of Lophophytum leandri"

F. Ungaro, R. d'Emmanuele di Villa Bianca, R. Sorrentino, A. Miro, F. Quaglia. (2012) "Dry powders based on PLGA nanoparticles for pulmonary delivery of antibiotics: Modulation of encapsulation efficiency, release rate and lung deposition pattern by hydrophilic polymers"

Ritieni A. (2012) "Durum wheat in conventional and organic farming: yield amount and pasta quality in Southern Italy. TheScientificWorldJOURNAL Article ID 973058, 9 pages,"

Ritieni A. (2012) "EFFECT OF CANOPY MANAGEMENT TECHNIQUES ON THE NUTRITIONAL QUALITY OF MONTEPULCIANO GRAPEVINE IN PUGLIA (SOUTHERN ITALY)"

Capasso R (2012) "Effects of St John's wort and its active constituents, hypericin and hyperforin, on isolated rat urinary bladder."

A. Romanelli (2012) "Effects of decoy molecules targeting NFkappaBtranscription factors in cystic fibrosis IB3-1 cellsRecruitment of NFkappaB to the IL-8 gene promoterand transcription of the IL-8 gene"

Russo R., Calignano A. (2012) "Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity."

E Novellino (2012) "Effects of polyphenol compounds on influenza A virus replication and definition of their mechanism of action"

R. d'Emmanuele di Villa Bianca, E. Mitidieri, P. Grieco, E. Novellino, G. Cirino, R. Sorrentino (2012) "Endogenous urotensin II selectively modulates erectile function through eNOS"

Ungaro F., Miro A., Quaglia F. (2012) "Engineered PLGA nano- and micro-carriers for pulmonary delivery: challenges and promises"

Carmine Ostacolo, Diana Tronino, Sonia Laneri, Antonia Sacchi (2012) "Enhancement of trans-corneal permeation of riboflavin-5'-phosphate from new ophthalmic solutions. A promising, non-invasive approach for corneal trans-ephithelial cross linking treatment"

C. Formisano, D. Rigano, F. Senatore (2012) "Essential oil composition and antibacterial activity of Anthemis mixta and A. tomentosa (Asteraceae)"

Sautebin L (2012) "Evaluation of cosmetic product exposures reported to the Milan Poison Control Centre, Italy from 2005 to 2010."

Maiuri M.C. (2012) "Evaluation of rapamycin-induced cell death."

Misso G (2012) "Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid"

Lembo F (2012) "Extensive molecular analysis of patients bearing CFTR-related disorders."

A. Zampella (2012) "Farnesoid-X-receptor from medicinal chemistry to clinical application"

PAGANO D (2012) "First synthesis of parazoanthine-A and its O-Me derivative"

C. Formisano, D. Rigano, F. Senatore (2012) "Flavonoids in Subtribe Centaureinae (Cass.) Dumort. (Tribe Cardueae, Asteraceae): Distribution and 13C-NMR Spectral Data"

Cosimelli B., Marinelli L., Novellino E., Greco G. (2012) "From the Pharmacophore to the Homology Model of the Benzodiazepine Receptor: The Indolyglyoxylamides Affair."

Lavecchia A. (2012) "Frontal affinity chromatography with MS detection of the ligand binding domain of PPAR¿ receptor: Ligand affinity screening and stereoselective ligand–macromolecule interaction"

Marialuisa Menna, Anna Aiello, Filomena D’Aniello, Concetta Imperatore (2012) "Further Investigation of the Mediterranean Sponge Axinella polypoides: Isolation of a New Cyclonucleoside and a New Betaine"

A. Santini, A. Ritieni (2012) "Fusaproliferin, beauvericin and enniatins: occurrence in food - a review"

Ritieni A. (2012) "Fusarium verticillioides from finger millet in Uganda"

Giancola C. (2012) "G-Qadruplexes from Human Telomeric DNA: How Many Conformations in PEG Containing Solutions?"

G. OLIVIERO, G. PICCIALLI (2012) "G-Quadruplex-Forming Oligonucleotide Conjugated to Magnetic Nanoparticles: Synthesis, Characterization, and Enzymatic Stability Assays"

Meli R (2012) "GW0742, a high-affinity PPAR-d agonist, mediates protection in an organotypicmodel of spinal cord damage"

Zampella A. (2012) "Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition"

Carmen Festa, Simona De Marino, Maria Valeria D'Auria, Angela Zampella (2012) "Gracilioethers E-J, new oxygenated polyketides from the marine sponge Plakinastrella mamillaris"

D. Marasco (2012) "HIV p24 as scaffold for presenting conformational HIV env antigens"

I Gomez-Monterrey (2012) "Heat Shock Protein 90 Inhibitors as Therapeutic Agents."

A. Zampella (2012) "Heat Shock Proteins as Key Biological Targets of the Marine Natural Cyclopeptide Perthamide C"

Lembo F (2012) "Helicobacter pylori regulates iNOS promoter by histone modifications in human gastric epithrlial cells"

P. Ciminiello, C. Dell’Aversano, E. Dello Iacovo, M. Forino, L. Tartaglione (2012) "High Resolution LC-MSn Fragmentation Pattern of Palytoxin as Template to Gain New Insights into Ovatoxin-a Structure. The Key Role of Calcium in MS Behavior of Palytoxins"

Lattanzi F. (2012) "High resolution investigation of the 7 mm region of the ethane spectrum"

A. Randazzo, E. Novellino (2012) "High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity"

Fattorusso C (2012) "Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives"

Grassia G, Ialenti A, Mascolo N, Cicala C (2012) "Hyperresponsiveness to adenosine in sensitized Wistar rats over-expressing A(1) receptor."

MELISI D, RIMOLI MG (2012) "Ibuprofen delivered by poly(lactic-co-glycolic acid) (PLGA) nanoparticles to human gastric cancer cells exerts antiproliferative activity at very low concentrations"

Marinelli L., La Pietra V., Novellino E. (2012) "Identification of Glycogen Synthase Kinase-3 Inhibitors with a Selective Sting for Glycogen Synthase Kinase-3a"

S Tomassi, S Di Maro, E Novellino (2012) "Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells"

E Novellino (2012) "Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1"

La Pietra V., Marinelli L., Novellino E. (2012) "Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: A first round of lead optimization."

Misso G (2012) "Immune-modulating effects of the newest cetuximab-based chemoimmunotherapy regimen in advanced colorectal cancer patients. "

R. Russo, G. Mattace Raso, R. Meli, A. Calignano (2012) "Implication of allopregnanolone in the antinociceptive effect of N-palmitoylethanolamide in acute or persistent pain."

Sautebin L, Rossi A (2012) "Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme"

Novellino E. (2012) "Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid CB1 Receptor"

Ritieni A. (2012) "Influence of different soluble dietary fibers on the bioaccessibility of the minor Fusarium mycotoxin beauvericin"

P. Ciminiello, C. Dell'Aversano, E. Dello Iacovo, M. Forino, L. Tartaglione (2012) "Influence of temperature and salinity on Ostreopsis cf. ovatagrowth and evaluation of toxin content through HR LC-MS andbiological assays"

Ritieni A. (2012) "Influence of the heat treatment on the degradation of the minor Fusarium mycotoxin beauvericin"

Cicala C (2012) "Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma."

Accardo A., Morelli G. (2012) "Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells"

Izzo AA, Capasso R, Borrelli F, Romano B (2012) "Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice"

N. Borbone, G. Oliviero, S. D'Errico (2012) "Insight Into the Conformational Arrangement of a Bis-THF DiolCompound Through 2D-NMR Studies and X-Ray StructuralAnalysis"

Giorgia Oliviero, Stefano D'Errico, Nicola Borbone (2012) "Insight into Pyridinium Chlorochromate Chemistry: Catalytic Oxidation of Tetrahydrofuran Compounds and Synthesis of Umbelactone"

Izzo A.A. (2012) "Interactions between herbs and conventional drugs: overview of the clinical data"

Galdiero S (2012) "Intracellular delivery: exploiting viral membranotropic peptides."

V. Limongelli, E. Novellino (2012) "Investigating the mechanism of substrate uptake and release in the glutamate transporter homologue Glt(Ph) through metadynamics simulations."

Nicola Borbone, Maria Rosaria Bucci, Giorgia Oliviero, Elena Morelli, Stefano D'Errico, Valentina Vellecco, Giuseppe cirino, Gennaro Piccialli, Caterina Fattorusso, * Michela Varra, et al. (2012) "Investigating the role of T7 and T12 residues on biological properties of Thrombin Binding Aptamer: enhancement of anticoagulant activity by a single nucleobase modification"

P. Ciminiello, C. Dell'Aversano, E. Dello Iacovo, M. Forino, L. Tartaglione (2012) "Isolation and Structure Elucidation of Ovatoxin-a, the Major Toxin Produced by Ostreopsis ovata"

A. Carotenuto, I. Gomez-Monterrey, E. Novellino (2012) "Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity"

Caliendo G, Santagada V, Perissutti E, Severino B, Fiorino F, Frecentese F (2012) "Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development"

Enrica Menditto (2012) "La prescrizione di antibiotici in regione Campania negli anni 2002-2011"

Menditto E., Orlando V. (2012) "Le politiche di compartecipazione alla spesa farmaceutica"

G. Chianese, O. Taglialatela Scafati (2012) "Leucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8"

L. Grumetto, F. Barbato (2012) "Lipophilic and electrostatic forces encoded in IAM-HPLC indexes of basic drugs: their role in membrane partition and their relationships with BBB passage data."

Miro A, Ungaro F, Quaglia F (2012) "Local delivery of the hemostatic agent tranexamic acid in chronically anticoagulated patients."

G. Chianese, R. Teta, O. Taglialatela Scafati (2012) "Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin"

D'Auria G, Falcigno L, Galdiero S (2012) "Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination."

M. V. D’Auria, A. Zampella (2012) "Marine sponge steroids as nuclear receptor ligands"

Bruno A (2012) "Membrane-Sensitive Conformational States of Helix 8 in the Metabotropic Glu2 Receptor, a Class C GPCR"

Perrone-Capano C (2012) "Methylphenidate administration determines enduringchanges in neuroglial network in rats."

Galdiero S (2012) "Microbe-host interactions: structure and role of Gram-negative bacterial porins. "

Santini A., Ritieni A. (2012) "Microwave-assisted exctraction of Ochratoxin A from roasted coffee: an alternative extraction approach"

E Novellino (2012) "Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents"

Valentina Sepe, Maria Valeria D'Auria, Angela Zampella (2012) "Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist"

Capasso R., Romano B., Borrelli F., Izzo A.A. (2012) "Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables: evidence for TRPA1-independent effects"

Bruno A (2012) "Molecular Dynamics Simulations of G Protein-Coupled Receptors"

Grieco P. (2012) "Molecular changes induced in rat liver by hemorrhage and effects of melanocortin treatment."

Misso G (2012) "Molecular targets for the treatment of multiple myeloma "

Rossi A, Sautebin L (2012) "Myrtucommulone from Myrtus communis: metabolism, permeability, and systemic exposure in rats"

De Napoli Lorenzo (2012) "N(3)-protection of thymidine with Boc for an easy synthetic access to sugar-alkylated nucleoside analogs"

Marinelli L, La Pietra V, Novellino E (2012) "N-O-ISOPROPYL SULFONAMIDO-BASED HYDROXAMATES: KINETIC CHARACTERISATION OF A SERIES OF MMP-12/MMP-13 DUAL TARGET INHIBITORS."

Galdiero S (2012) "NF-¿B as a potential therapeutic target in microbial diseases."

De Rosa G, Salzano G (2012) "Nanotech Revolution for the Anti-Cancer Drug Delivery through Blood-Brain-Barrier."

De Rosa G, Salzano G (2012) "Nanotechnologies: a strategy to overcome blood-brain barrier"

L. Ferrara (2012) "Nasunina: un colorante naturale."

D'Auria M.V., Sepe V., Zampella A. (2012) "Natural ligands for nuclear receptors: biology and potential therapeutic applications"

E Novellino (2012) "New Nitrogen Containing Substituents at the Indole-2-carboxamide Yield High Potent and Broad Spectrum Indolylarylsulfone HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors"

F. Fiorino, B. Severino, E. Perissutti, F. Frecentese, A. Ciano, V. Santagada, G. Caliendo (2012) "New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation"

Giorgia Oliviero, Nicola Borbone, Stefano D'Errico, Luciano Mayol, Gennaro Piccialli (2012) "New anti-HIV aptamers based on tetra-end-linked DNA G-quadruplexes: effect of the base sequence on anti-HIV activity"

Imperatore C, Aiello A, D'Aniello F, Meli R, Mattace Raso G, Menna M (2012) "New bioactive alkyl sulfates from mediterranean tunicates."

M. Biondi (2012) "New insights into the mechanisms of the interactions between doxorubicin and the ion-exchange hydrogel DC Bead™ for use in transarterial chemoembolization (TACE)."

Marasco D. (2012) "New mimetic peptides of Kinase Inhibitory Region (KIR) of SOCS1 through focused peptide libraries"

Romanelli A (2012) "New perspectives for natural antimicrobial peptides: application as antinflammatory drugs in a murine model."

Salzano G, De Rosa G (2012) "New self-assembly nanoparticles and stealth liposomes for the delivery of zoledronic acid: a comparative study"

P. Ciminiello, C. Dell’Aversano, E. Dello Iacovo, L. Tartaglione (2012) "Nitrogen and phosphorus limitation effects on cell growth, biovolume, and toxin production in Ostreopsis cf. ovata"

Antonella Virgilio, Veronica Esposito, Aldo Galeone (2012) "Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer"

S. De Marino, C. Festa, F. Zollo (2012) "Novel steroidal components from the underground parts of Ruscus aculeatus L."

Marasco D (2012) "Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells"

Tenore G. C., Novellino E. (2012) "Nutraceutical potential and antioxidant benefits of red pitaya (Hylocereus polyrhizus) extracts"

Tenore G.C., Ritieni A., Novellino E. (2012) "Nutraceutical potential of monofloral honeys produced by the Sicilian black honeybees (Apis mellifera ssp. sicula)"

Ritieni A. (2012) "Ochratoxin A adsorption phenotype: an inheritable yeast trait"

Rossi A, Sautebin L (2012) "On the inhibition of 5-lipoxygenase product formation by tryptanthrin: mechanistic studies and efficiency in vivo."

E Novellino (2012) "Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling"

Francesca Ungaro, Agnese Miro, Raffaella Sorrentino, Rosa Carnuccio, Fabiana Quaglia (2012) "PEI-Engineered Respirable Particles Delivering a Decoy Oligonucleotide to NF-kB: Inhibiting MUC2 Expression in LPS-Stimulated Airway Epithelial Cells"

Grieco P. (2012) "PI3K¿ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism."

G. Salzano, G. De Rosa (2012) "PLGA microspheres encapsulating siRNA anti-TNFalpha: Efficient RNAi-mediated treatment of arthritic joints."

Lembo F (2012) "POZ-, AT-hook-, and Zinc Finger-containing Protein (PATZ) Interacts with Human Oncogene B Cell Lymphoma 6 (BCL6) and Is Required for Its Negative Autoregulation."

Russo R, Avagliano C, Meli R, Calignano A. (2012) "Palmitoylethanolamide Protects Against the Amyloid-ß25-35-Induced Learning and Memory Impairment in Mice, an Experimental Model of Alzheimer Disease."

P. Ciminiello, C. Dell'Aversano, M. Forino, L. Tartaglione (2012) "Palytoxin and an Ostreopsis Toxin Extract Increase the Levels of mRNAs Encoding Inflammation-Related Proteins in Human Macrophages via p38 MAPK and NF-¿B"

Accardo A, Cicala C, Tesauro D, De Rosa G, Morelli G (2012) "Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: a potential theranostic agent."

Galdiero S. (2012) "Peptides complementary to the active loop of porin P2 from Haemophilus influenzae modulate its activity."

Santini A. (2012) "Phomentrioloxin: a phytotoxic pentasubstituted geranylcyclohexentriol produced by Phomopsis sp., a potential mycoherbicide for Carthamus lanatus biocontrol"

Ritieni A. (2012) "Photo-selective hail nets affect fruit size and quality in Hayward kiwifruit"

Ritieni A. (2012) "Phylogenetic analyses and toxigenic profiles of Fusarium equiseti and Fusarium acuminatum isolated from cereals from Southern Europe"

C. Formisano, D. Rigano, F. Senatore (2012) "Phytochemical Profile and Apoptotic Activity of Onopordum cynarocephalum"

Carmen Festa, Simona De Marino, Maria Valeria D'Auria, Angela Zampella (2012) "Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of Peroxisome Proliferator-Activated Receptor gamma"

G. Grassia, A. Ialenti, P. Maffia (2012) "Plasmacytoid Dendritic Cells Play a Key Role in Promoting Atherosclerosis in Apolipoprotein E-Deficient Mice"

O. Taglialatela Scafati (2012) "Polyhydroxylated sterols from the Indonesian soft coral Sinularia sp. and their effect on farnesoid X-activated receptor"

V. Sepe, M. V. D'Auria, O. Taglialatela Scafati, S. De Marino, A. Zampella (2012) "Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei"

La Pietra V, Di Maro S, Giustiniano M, Marinelli L, Novellino E (2012) "Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step."

F. Borrelli, B. Romano, O. Taglialatela Scafati, R. Capasso, A. A. Izzo (2012) "Prokinetic effect of a standardized yarrow (Achillea millefolium) extract and its constituent choline: studies in the mouse and human stomach"

L Marinelli, V La Pietra, E Novellino (2012) "Protein Flexibility in Virtual Screening: The BACE-1 Case Study"

E Menditto (2012) "Proton pump inhibitors prescribing following the introduction of generic drugs"

D. Rigano (2012) "Psidium guajava L. anti-neoplastic effects: induction of apoptosis and cell differentiation"

Ritieni A. (2012) "Quantification of the relationship between the environment and Fusarium head blight, Fusarium pathogen density, and mycotoxins in winter wheat in Europe"

Zampella A., D'Auria M.V. (2012) "Quantitative NMR-Derived Interproton Distances Combined with Quantum Mechanical Calculations of 13C Chemical Shifts in the Stereochemical Determination of Conicasterol F, a Nuclear Receptor Ligand from Theonella swinhoei"

E Novellino (2012) "Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1"

Ritieni A. (2012) "Reduction in vitro of the minor Fusarium mycotoxin beauvericin employing different strains of probiotic bacteria"

C. Irace (2012) "Ruthenium-based complex nanocarriers forcancer therapy"

O. Taglialatela Scafati, G. Chianese (2012) "STAT-3 inhibitory bisabolanes from Carthamus glaucus"

Capasso R, Izzo AA (2012) "Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection."

V. Limongelli, S. Cosconati (2012) "Sampling protein motion and solvent effect during ligand binding."

O. Taglialatela Scafati, G. Chianese (2012) "Sesquiterpenoids from common ragweed (Ambrosia artemisiifolia L.), an invasive biological polluter"

Pagano B., Lauri I., Giustiniano M., Marinelli L., Giancola C., Novellino E., Randazzo A. (2012) "Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death"

d'Emmanuele di Villa Bianca R, Mitidieri E, Cirino G, Sorrentino R (2012) "Sildenafil Effect on the Human Bladder Involves the L-cysteine/Hydrogen Sulfide Pathway: A Novel Mechanism of Action of Phosphodiesterase Type 5 Inhibitors"

A. Ianaro, E. Panza, O. Taglialatela Scafati (2012) "Sinularioside, a triacetylated glycolipid from the Indonesian soft coral Sinularia sp., is an inhibitor of NO release"

Ianaro A, Panza E, Taglialatela Scafati O (2012) "Sinulasulfoxide and sinulasulfone, sulfur-containing alkaloids from the Indonesian soft coral Sinularia sp."

A. Romanelli (2012) "Site-specific protein double labeling by expressed protein ligation: applications to repeat proteins"

Falcigno L. (2012) "Small Peptide Inhibitors of Acetyl-Peptide Hydrolase Having an Uncommon Mechanism of Inhibition and a Stable Bent Conformation"

Marasco D (2012) "Solution structure of the first Sam domain of Odin and binding studies with the EphA2 receptor"

Pagano B., Marinelli L., La Pietra V., Lauri I., Novellino E., Giancola C., Randazzo A. (2012) "State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders"

Patrizia Ciminiello, Carmela Dell'Aversano, Martino Forino, Luciana Tartaglione (2012) "Stereochemical Studies on Ovatoxin-a"

Antonella Virgilio, Veronica Esposito, Aldo Galeone (2012) "Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes"

Virgilio A, Esposito V, Mayol L, Galeone A (2012) "Structural Investigations on the Anti-HIV G-Quadruplex-Forming Oligonucleotide TGGGAG and Its Analogues: Evidence for the Presence of an A-Tetrad"

Galdiero S (2012) "Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system."

Ritieni A. (2012) "Study of thermal resistance and in vitro bioaccessibility of patulin from artificially contaminated apple products"

Pagano B., Giancola C. (2012) "Studying the effect of crowding and dehydration on DNA G-quadruplexes"

Greco, Novellino (2012) "Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein."

Marinelli L, Novellino E (2012) "Synthesis and Biological Evaluation of CTP Synthetase Inhibitors as Potential Agents for the Treatment of African Trypanosomiasis."

S. D'Errico, G. Oliviero, N. Borbone, L. Mayol, G. Piccialli (2012) "Synthesis and biological evaluation of unprecedented ring-expanded nucleosides (RENs) containing the imidazo[4,5-d][1,2,6]oxadiazepine ring system."

PAGANO D (2012) "Synthesis of Phidianidine B, a highly cytotoxic 1,2,4-oxadiazole marine metabolite"

F. Fiorino, B. Severino, E. Perissutti, A. Ciano, F. Frecentese, V. Santagada, G. Caliendo (2012) "Synthesis of benzamide derivatives and their evaluation as antiprion agents"

Lavecchia A., Novellino E. (2012) "Synthesis, biological evaluation and molecular investigation of fluorinated peroxisomes proliferator-activated receptors a/¿ dual agonists"

Lavecchia A. (2012) "Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity"

C. Irace (2012) "Synthesis, self-aggregation and bioactivity properties of a cationic aminoacyl surfactant, based on a new class of highly functionalized nucleolipids"

L. Marinelli, V. Limongelli, E. Novellino (2012) "Tailoring of integrin ligands: probing the charge capability of the metal ion-dependent adhesion site."

Carnuccio R, Maiuri MC (2012) "Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ¿F508 cystic fibrosis transmembrane conductance regulator"

A. Romanelli (2012) "Targeting pre-miRNA by Peptide Nucleic Acids: A new strategy to interfere in the miRNA maturation."

Valeria Costantino, Alfonso Mangoni, Roberta Teta, Elisabetta Panza, Angela Ianaro (2012) "Tedarenes A and B: Structural and Stereochemical Analysis of Two New Strained Cyclic Diarylheptanoids from the Marine SpongeTedania ignis"

O. Taglialatela Scafati (2012) "The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system"

Valentina Sepe, Maria Valeria D'Auria, Angela Zampella (2012) "The First Total Synthesis of Solomonsterol B, a Marine Pregnane X Receptor Agonist"

Rossi F. (2012) "The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis and binding studies"

Virgilio A, Esposito V, Giancola C, Galeone A (2012) "The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view"

Menditto E. (2012) "The burden of hospitalization related to diabetes mellitus: A population-based study."

VIRGILIO A., ESPOSITO V., MAYOL L., GALEONE A. (2012) "The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands"

Marasco D. (2012) "The intrinsic stability of the human prion b-sheet region investigated by molecular dynamics"

Rossi A., Sautebin L. (2012) "The novel Sinupret® dry extract exhibits anti-inflammatory effectiveness in vivo"

Bucci M, Cirino G (2012) "Thioglycine and l-thiovaline: biologically active H2S-donors."

G. D’Auria, L. Falcigno (2012) "Toward a better understanding of the interaction between TGF-ßfamily members and their ALK receptors"

P. Ciminiello, C. Dell'Aversano, M. Forino, L. Tartaglione (2012) "Toxin levels and profiles in microalgae from the North-Western Adriatic sea-15 years of studies on cultured species"

P. Ciminiello, C. Dell’Aversano, E. Dello Iacovo, M. Forino, L. Tartaglione (2012) "Toxin-Producing Ostreopsis cf. ovata are Likely to Bloom Undetectedalong Coastal Areas"

Agnese Miro, Francesca Ungaro, Fabiana Quaglia (2012) "Triamcinolone solubilization by (2-hydroxypropyl)-ß-cyclodextrin: a spectroscopic and computational approach"

Misso G, Salzano G, De Rosa G (2012) "Tumour-Specific Uptake of Anti-Cancer Drugs: The Future is Here"

Ettore Novellino (2012) "Tuning RNA Interference by Enhancing siRNA/PAZ Recognition"

P. Ciminiello, C. Dell’Aversano, E. Dello Iacovo, M. Forino, L. Tartaglione (2012) "Unique Toxin Profile of a Mediterranean Ostreopsis cf. ovata Strain:HR LC-MSn Characterization of Ovatoxin-f, a New Palytoxin Congener"

L. Ferrara, A. Santini (2012) "Vanilla planifolia Andr.: un aromatizzante naturale impiegato nel settore alimentare, farmaceutico e cosmetico."

Di Maro S, Marinelli L, Novellino E. (2012) "Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A(3) Adenosine Receptor Antagonists"

Bucci M, Vellecco V, Cirino G. (2012) "cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation."

A. Romanelli (2012) "gamma sulphate PNA (PNA S): Highly Selective DNA Binding Molecule Showing Promising Antigene Activity"

Misso G (2012) "miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1. "

A. Romanelli (2012) "ß-Hairpin stabilization through an interstrand triazole bridge"

Izzo A.A. (2012) "Limited value of traditional Chinese medicine in improving quality of life in cancer patients"

Carnuccio R, Maiuri MC (2012) "Nanomaterials toxicity and cell death modalities."

E. Menditto (2012) "A Large-Scale Longitudinal Population-Based Study of Risk Reduction of Cardiovascular Complications in Patients on Bolus Insulin Analogues"

E. Menditto (2012) "A Ten Years Longer Life: A Therapeutic Education Program for Hypertensive Patients"

Tenore G, Ritieni A, Novellino E (2012) "Annurca apple (M. pumila Miller cv Annurca): bioactive polyphenols."

Gian Carlo Tenore, Isabel Maria Gomez Monterrey (2012) "Antioxidant and oxidative effects of grape juices"

Gian Carlo Tenore, Isabel Maria Gomez Monterrey (2012) "Antioxidant profile and in vitro antiproliferative and cardioprotective properties of typical red and white wines from vineyards cultivated in Scafati (Salerno, Italy)"

Carmen Formisano, Daniela Rigano, Felice Senatore, Gian Carlo Tenore (2012) "Antioxidant properties and anti-neoplastic effects of purple-fleshed potatoes"

Gian Carlo Tenore (2012) "Antioxidants in berry skin and wine of Vitis vinifera L. cv. Aglianico (Basilicata, Italy)"

Tesauro D., Accardo A., Morelli G. (2012) "Comparison of serum stability and cellular binding properties of 8 DOTA-coupled Bombesin receptor targeting peptides"

Gian Carlo Tenore (2012) "Conformational study and identification of milk caseins"

G Mattace Raso, RD’Emmanuele di Villa Bianca, E Mitidieri, R Meli, R Sorrentino (2012) "Contribute of the L-cysteine/ H2S pathway in placenta homeostasis in hypertensive disorders"

Mitidieri E (2012) "Hydrogen sulphide enhances human platelet aggregation through phospholipase A2 activation"

G. Chianese, C. Fattorusso, M. Persico, O. Taglialatela Scafati (2012) "Marine endoperoxides as antiprotozoan lead compounds"

D'Auria M.V., De Marino S., Sepe V., Zampella A. (2012) "Marine natural products as modulators of nuclear receptors"

Ianaro A, Panza E, Bucci M, Cirino G (2012) "Pro-apoptotic effect of hydrogen sulphide in human melanoma cell lines: A signal transduction analysis"

O. Taglialatela Scafati, G. Chianese (2012) "Sesquiterpenoids from common ragweed (Ambrosia artemisiifolia L.), an invasive biological polluter"

Zampella A. (2012) "a Farnesoid-X-Receptor (FXR)-Glucocorticoid Receptor (GR) Cascade Regulates Intestinal Innate Immunity in Response to FXR Activation"

Mitidieri E (2012) "cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation"

Emma Mitidieri, Roberta d’Emmanuele di Villa Bianca, Raffaella Sorrentino (2012) "l-Cysteine/H2S pathway involvement in human platelet aggregation"